Recent kala-azar cases in India: isozyme profiles of Leishmania parasites.

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dc.contributor.authorChatterjee, Men_US
dc.contributor.authorManna, Men_US
dc.contributor.authorBhaduri, A Nen_US
dc.contributor.authorSarkar, Den_US
dc.date.accessioned1995-10-01en_US
dc.date.accessioned2009-05-27T07:59:31Z
dc.date.available1995-10-01en_US
dc.date.available2009-05-27T07:59:31Z
dc.date.issued1995-10-01en_US
dc.description.abstractIn this study, three WHO recommended reference strains of Leishmania donovani (DD8), L. tropica (K27) and L. major (5 ASKH) were compared by isozyme analysis of 9 soluble enzymes using cellulose acetate electrophoresis (CAE). The isozyme profile of the three species showed distinct electrophoretic mobilities of the enzymes studied. This technique was applied to study the enzyme patterns of 8 clinical isolates of visceral leishmaniasis (VL) and two post kala-azar dermal leishmaniasis (PKDL) collected from the present epidemic (1990s to date). They were seen to be similar to the two isolates of the 1970s epidemic. Interspecies differences were observed in different reference Leishmania species whereas no intraspecies difference was observed amongst the clinical isolates (8VL + 2PKDL) and all of these were found to be similar to L. donovani isolates of 1970s epidemic.en_US
dc.description.affiliationLeishmania Division, Indian Institute of Chemical Biology, Calcutta.en_US
dc.identifier.citationChatterjee M, Manna M, Bhaduri AN, Sarkar D. Recent kala-azar cases in India: isozyme profiles of Leishmania parasites. Indian Journal of Medical Research. 1995 Oct; 102(): 165-72en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/22839
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshIsoenzymes --analysisen_US
dc.subject.meshLeishmania --enzymologyen_US
dc.subject.meshLeishmaniasis, Visceral --parasitologyen_US
dc.subject.meshPilot Projectsen_US
dc.titleRecent kala-azar cases in India: isozyme profiles of Leishmania parasites.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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