Prevalence of high-risk human papilloma virus types and cervical smear abnormalities in female sex workers in Chandigarh, India.

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dc.contributor.authorSingh, M P
dc.contributor.authorKaur, M
dc.contributor.authorGupta, N
dc.contributor.authorKumar, A
dc.contributor.authorGoyal, K
dc.contributor.authorSharma, A
dc.contributor.authorMajumdar, M
dc.contributor.authorGupta, M
dc.contributor.authorRatho, R K
dc.date.accessioned2016-08-16T09:57:26Z
dc.date.available2016-08-16T09:57:26Z
dc.date.issued2016-07
dc.description.abstractPurpose: Cervical cancer is the most common cancer among women in developing nations. Nearly 90% of the cases have been linked to the presence of high-risk human papillomavirus (hrHPV) types 16 and 18. The risk of cervical cancer may be high in female sex workers (FSWs) due to multiple sexual partners. This study aimed to determine the prevalence of cytological abnormalities and hrHPV types 16 and 18 in FSWs in Chandigarh, North India using the liquid-based cytology (LBC) approach. Materials and Methods: The cervical brush samples were collected from 120 FSW and 98 age-matched healthy controls (HCs). These were subjected to pap smear using conventional method, LBC and the detection of hrHPV types 16 and 18 was carried out using polymerase chain reaction. Results: The LBC samples showed better cytological details and also reduced the number of unsatisfactory smears from 11% in Pap to 1.5% in the LBC. A significantly higher number of inflammatory smears were reported in FSWs (51.7% vs. 34.7%, P = 0.01). The hrHPV types 16/18 were detected in 33/120 (27.5%) FSW versus 23/98 (23.5%) HCs. The risk of acquiring hrHPV was higher in FSWs, who had age at first sex ≤25 years, higher income and the habit of smoking. Conclusion: The high prevalence of hrHPV among FSWs and HCs suggests the need for the implementation of effective National Screening Programme for early detection of hrHPV types to decrease the burden of cervical cancer, especially in high-risk population.en_US
dc.identifier.citationSingh M P, Kaur M, Gupta N, Kumar A, Goyal K, Sharma A, Majumdar M, Gupta M, Ratho R K. Prevalence of high-risk human papilloma virus types and cervical smear abnormalities in female sex workers in Chandigarh, India. Indian Journal of Medical Microbiology. 2016 July-Sept; 34(3): 328-334.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/176669
dc.language.isoenen_US
dc.source.urihttps://www.ijmm.org/article.asp?issn=0255-0857;year=2016;volume=34;issue=3;spage=328;epage=334;aulast=Singhen_US
dc.subjectCervical canceren_US
dc.subjectfemale sex workersen_US
dc.subjecthuman papillomavirusen_US
dc.subjectliquid based cytologyen_US
dc.titlePrevalence of high-risk human papilloma virus types and cervical smear abnormalities in female sex workers in Chandigarh, India.en_US
dc.typeArticleen_US
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