A study of dapsone syndrome at a rural teaching hospital in South India.

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Date
2001-03-01
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Abstract
Dapsone syndrome or sulphone syndrome was noticed within four to six weeks of starting treatment in 10 out of 604 patients (1.6%) on MDT for leprosy treated at Rajah Muthiah Medical College Hospital, South Arcot District, Tamil Nadu State during the period 1995-1998. Patients developed either maculo papular rash or exfoliation along with fever and lymphadenopathy. Abnormal liver function tests were noticed in 50%. The patients with dapsone syndrome were treated with corticosteriods after withdrawing dapsone. There was complete resolution of skin lesions and other symptoms.
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Prasad PV. A study of dapsone syndrome at a rural teaching hospital in South India. Indian Journal of Dermatology, Venereology and Leprology. 2001 Mar-Apr; 67(2): 69-71
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https://imsear.searo.who.int/handle/123456789/52989
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Indian Journal of Dermatology, Venereology and Leprology