In vitro activity of antimicrobial agents against oxacillin resistant staphylococci with special reference to Staphylococcus haemolyticus.

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dc.contributor.authorChaudhury, Aen_US
dc.contributor.authorKumar, A Gen_US
dc.date.accessioned2007-01-23en_US
dc.date.accessioned2009-05-28T09:05:55Z
dc.date.available2007-01-23en_US
dc.date.available2009-05-28T09:05:55Z
dc.date.issued2007-01-23en_US
dc.description.abstractOne hundred and sixty seven isolates of staphylococci isolated from the inpatients of a tertiary care referral hospital in South India were speciated and activity of oxacillin, glycopeptides, linezolid and quinupristin/dalfopristin against these isolates was tested by broth microdilution method. Of the 114 coagulase negative staphylococci (CoNS), 49.1 % were S. haemolyticus, isolated predominantly from urine (64.6%), while the rest belonged to 11 other species. More than half the isolates of S. aureus (52.8%) and 68.4% of the CoNS were oxacillin resistant. All the strains were uniformly susceptible to vancomycin, linezolid and quinupristin/dalfopristin; but 25.6% isolates of S. haemolyticus showed reduced susceptibility to teicoplanin (MIC: 8-16 mg/L). Our study demonstrates the high prevalence of oxacillin resistance among hospital isolates of S. aureus and CoNS in India. Vancomycin, along with the newer agents like linezolid and quinupristin/dalfopristin remains the drug of choice for treating multi drug resistant staphylococcal infections.en_US
dc.description.affiliationDepartment of Microbiology, SV University of Medical Sciences, Tirupati, Andhra Pradesh, India. abhijitch2001@yahoo.co.inen_US
dc.identifier.citationChaudhury A, Kumar AG. In vitro activity of antimicrobial agents against oxacillin resistant staphylococci with special reference to Staphylococcus haemolyticus. Indian Journal of Medical Microbiology. 2007 Jan; 25(1): 50-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53427
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.subject.meshAcetamides --pharmacologyen_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshDrug Resistance, Multiple, Bacterialen_US
dc.subject.meshIndiaen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshOxacillin --pharmacologyen_US
dc.subject.meshOxazolidinones --pharmacologyen_US
dc.subject.meshStaphylococcus --drug effectsen_US
dc.subject.meshStaphylococcus haemolyticus --drug effectsen_US
dc.subject.meshTeicoplanin --pharmacologyen_US
dc.subject.meshVancomycin --pharmacologyen_US
dc.subject.meshVirginiamycin --analogs & derivativesen_US
dc.titleIn vitro activity of antimicrobial agents against oxacillin resistant staphylococci with special reference to Staphylococcus haemolyticus.en_US
dc.typeJournal Articleen_US
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