Electrocardiographic abnormalities in aluminium phosphide poisoning with special reference to its incidence, pathogenesis, mortality and histopathology.

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dc.contributor.authorChugh, S Nen_US
dc.contributor.authorChugh, Ken_US
dc.contributor.authorRam, Sen_US
dc.contributor.authorMalhotra, K Cen_US
dc.date.accessioned1991-02-01en_US
dc.date.accessioned2009-05-31T10:40:37Z
dc.date.available1991-02-01en_US
dc.date.available2009-05-31T10:40:37Z
dc.date.issued1991-02-01en_US
dc.description.abstractNinety-five patients out of total 190 cases of aluminium phosphide (ALP) poisoning, who exhibited ECG changes were studied for incidence, type and pattern of ECG abnormalities, their effect on mortality and their relationship with histopathology of heart. Its incidence in the present study was 50%. The arrhythmias, conduction disturbances and ischaemic pattern occurred more or less in equal frequency. Certain ECG abnormalities which had not been reported previously ie, early repolarisation syndrome, varied sino-atrial blocks, bradycardia-tachycardia syndrome and electrical alternans were observed in this study. The clinical profile of these cases was similar irrespective of whether patients had ECG abnormalities or not. Shock was the cardinal feature. There was no effect of ECG abnormalities on mortality. The mortality which was otherwise high, depended upon severity of poisoning, dose of poison consumed, duration of shock, failure of response of shock to resuscitative measures and severe hypomagnesaemia. The pathogenesis of ECG abnormalities is still obscure. Hypomagnesaemia was observed in all the 18 cases studied, irrespective of ECG abnormalities. However, these were common when hypomagnesaemia was severe. Hypoxaemia and shock were not the contributory factors for these abnormalities. Autopsy revealed stereotyped histopathological changes of toxic myocarditis independent of ECG findings.en_US
dc.description.affiliationMedical College and Hospital, Rohtak.en_US
dc.identifier.citationChugh SN, Chugh K, Ram S, Malhotra KC. Electrocardiographic abnormalities in aluminium phosphide poisoning with special reference to its incidence, pathogenesis, mortality and histopathology. Journal of the Indian Medical Association. 1991 Feb; 89(2): 32-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/99597
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAluminum Compoundsen_US
dc.subject.meshElectrocardiographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Diseases --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMortalityen_US
dc.subject.meshPesticides --poisoningen_US
dc.subject.meshPhosphines --poisoningen_US
dc.subject.meshPoisoning --complicationsen_US
dc.titleElectrocardiographic abnormalities in aluminium phosphide poisoning with special reference to its incidence, pathogenesis, mortality and histopathology.en_US
dc.typeJournal Articleen_US
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