Cysticercus immunoblot assay in patients with single, small enhancing lesions and multilesional neurocysticercosis.

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dc.contributor.authorSingh, Gen_US
dc.contributor.authorKaushal, Ven_US
dc.contributor.authorRam, Sen_US
dc.contributor.authorKaushal, R Ken_US
dc.contributor.authorDhanuka, A Ken_US
dc.contributor.authorKhurana, Sen_US
dc.date.accessioned1999-05-25en_US
dc.date.accessioned2009-05-30T22:55:03Z
dc.date.available1999-05-25en_US
dc.date.available2009-05-30T22:55:03Z
dc.date.issued1999-05-25en_US
dc.description.abstractA single, small (< 20 mm), ring or disc shaped contrast enhancing lesion located at the cortical-subcortical junction with minimal or no surrounding edema on computed tomography is the commonest mode of presentation of neurocysticercosis in the Indian subcontinent. Serum samples of 37 patients with these single, small enhancing lesions (SSEL's) and five patients with typical multilesional parenchymal neurocysticercosis were tested by the electro-immunoblot transfer (EITB) assay and the enzyme linked immunosorbent assay (ELISA). EITB was positive in 18 patients (48.64%) and ELISA was positive in 21 patients (56.76%) with SSEL's. On the other hand EITB was positive in all five patients (100%) and ELISA was positive in four patients (80%) with multilesional neurocysticercosis. The low sensitivity of the EITB in the SSEL's is probably linked to an insufficient immune stimulation provided by a single cysticercus cyst.en_US
dc.description.affiliationDept of Neurology, Dayanand Medical College, Ludhiana, India.en_US
dc.identifier.citationSingh G, Kaushal V, Ram S, Kaushal RK, Dhanuka AK, Khurana S. Cysticercus immunoblot assay in patients with single, small enhancing lesions and multilesional neurocysticercosis. Journal of the Association of Physicians of India. 1999 May; 47(5): 476-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/89957
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoblottingen_US
dc.subject.meshNeurocysticercosis --blooden_US
dc.titleCysticercus immunoblot assay in patients with single, small enhancing lesions and multilesional neurocysticercosis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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