Growth hormone in turner syndrome.

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dc.contributor.authorKhadilkar, V Ven_US
dc.contributor.authorKhadilkar, A Ven_US
dc.contributor.authorNandy, Men_US
dc.contributor.authorMaskati, G Ben_US
dc.date.accessioned2006-03-06en_US
dc.date.accessioned2009-05-27T05:20:48Z
dc.date.available2006-03-06en_US
dc.date.available2009-05-27T05:20:48Z
dc.date.issued2006-03-06en_US
dc.description.abstractWe assessed the effect of one year of therapy with recombinant Human Growth Hormone (rhGH) on growth velocity of 16 Indian girls with Turner Syndrome (TS) in a prospective, open trial. Patients received rhGH in a dose of 1 IU (0.3 mg)/kg/week. The mean pretreatment height was 117.1 cms (Z score minus 3.4), height velocity was 3.8 cm per year (Z score minus 2.4), and predicted height was 140 cm. At the end of therapy mean height was 123.9 (Z score minus 3.1), height velocity was 6.7 cm per year (Z score + 1.7), and the predicted height was 142.4 cm. The increment in height velocity with growth hormone therapy was statistically significant (P value = 0.001) and the mean increment in predicted height was 2.4 cm. Our study shows that girls with TS in India benefit from therapy with rhGH.en_US
dc.description.affiliationGrowth and Pediatric Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, 32, Sassoon Road, Pune 411 00, Maharashtra, India. akhadilkar@vsnl.neten_US
dc.identifier.citationKhadilkar VV, Khadilkar AV, Nandy M, Maskati GB. Growth hormone in turner syndrome. Indian Pediatrics. 2006 Mar; 43(3): 236-40en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/10186
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshGrowth --drug effectsen_US
dc.subject.meshHuman Growth Hormone --therapeutic useen_US
dc.subject.meshHumansen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRecombinant Proteinsen_US
dc.subject.meshTurner Syndrome --drug therapyen_US
dc.titleGrowth hormone in turner syndrome.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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