Reversible posterior leukoencephalopathy caused by azathioprine in systemic lupus erythematosus.

Foocharoen, Chingching; Tiamkao, Somsak; Srinakarin, Jiraporn; Chamadol, Nittaya; Sawanyawisuth, Kittisak

Reversible posterior leukoencephalopathy caused by azathioprine in systemic lupus erythematosus.

Date

2006-07-03

Authors

Foocharoen, Chingching

Tiamkao, Somsak

Srinakarin, Jiraporn

Chamadol, Nittaya

Sawanyawisuth, Kittisak

Abstract

The authors report a case of systemic lupus erythematosus with posterior leukoencephalopathy who presented with headache, tonic-clonic seizure, loss of consciousness and bilateral loss of vision, after taking azathioprine for three weeks. The patient had hypertension with normal eye grounds. The brain CT showed a hypodensity lesion at both bilateral occipital lobes, mainly in the white matter The symptoms and follow-up MRI were improved after the control of hypertension and discontinuation of azathioprine.

Description

Chotmaihet Thangphaet.

Citation

Foocharoen C, Tiamkao S, Srinakarin J, Chamadol N, Sawanyawisuth K. Reversible posterior leukoencephalopathy caused by azathioprine in systemic lupus erythematosus. Journal of the Medical Association of Thailand. 2006 Jul; 89(7): 1029-32