Helicobacter pylori infection in chronic smokers with non ulcer dyspepsia.

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dc.contributor.authorRajashekhar, Ven_US
dc.contributor.authorBhasin, D Ken_US
dc.contributor.authorRay, Pen_US
dc.contributor.authorVaiphei, Ken_US
dc.contributor.authorSharma, B Cen_US
dc.contributor.authorSingh, Ken_US
dc.date.accessioned2000-04-06en_US
dc.date.accessioned2009-06-04T04:48:14Z
dc.date.available2000-04-06en_US
dc.date.available2009-06-04T04:48:14Z
dc.date.issued2000-04-06en_US
dc.description.abstractBACKGROUND/AIMS: Both H. pylori infection and smoking are risk factors for acid peptic disorders. There is paucity of data on relationship between smoking and H. pylori infection. Therefore, we studied prevalence of H. pylori infection in smokers with non-ulcer dyspepsia (NUD). PATIENTS AND METHODS: 30 smokers with NUD (age 29.5 +/- 1.2 years; all men) and 30 non-smokers with NUD (age 29.2 +/- 1.6 years; all men) were included. None was on antiulcer drugs or antibiotics for more than 2 weeks. Upper gastrointestinal endoscopy was performed and antral biopsies obtained were subjected to rapid urease test, Gram's staining, culture and histopathology. Patient was considered H. pylori positive, if culture was positive or combination of histopathology plus rapid urease test or Gram's staining plus rapid urease test was positive. RESULTS: 24 of 30 (80%) smokers and 13 of 30 (43%) non smokers were positive for H. pylori infection (p < 0.001). There was no significant difference in the positivity of H. pylori in light (78%), moderate (81%) and heavy smokers (80%). All the 37 patients who were positive for H. pylori had histological gastritis compared to 65% in H. pylori negative patients. However there was no difference in presence of histological gastritis among H. pylori negative smokers (33%) and non smokers (70%; p = NS). CONCLUSIONS: H. pylori infection is more common in smokers with NUD than in non-smokers. However duration and amount of smoking has no relationship with H. pylori positivity.en_US
dc.description.affiliationPostgraduate Institute of Medical Education and Research, Chandigarh, India.en_US
dc.identifier.citationRajashekhar V, Bhasin DK, Ray P, Vaiphei K, Sharma BC, Singh K. Helicobacter pylori infection in chronic smokers with non ulcer dyspepsia. Tropical Gastroenterology. 2000 Apr-Jun; 21(2): 71-2en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/125158
dc.language.isoengen_US
dc.source.urihttps://www.tropicalgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshDyspepsia --etiologyen_US
dc.subject.meshHelicobacter Infections --epidemiologyen_US
dc.subject.meshHelicobacter pylorien_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSmoking --adverse effectsen_US
dc.titleHelicobacter pylori infection in chronic smokers with non ulcer dyspepsia.en_US
dc.typeJournal Articleen_US
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