Possible role of lens collagen in cataractogenesis.

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dc.contributor.authorMishra, Gen_US
dc.contributor.authorDas, G Ben_US
dc.contributor.authorBehera, H Nen_US
dc.date.accessioned1997-12-06en_US
dc.date.accessioned2009-05-29T09:22:01Z
dc.date.available1997-12-06en_US
dc.date.available2009-05-29T09:22:01Z
dc.date.issued1997-12-06en_US
dc.description.abstractThe solubility characteristics of collagen in human cataractous eye lenses were studied in relation to age. Post-operative cataractous lenses were collected form eye camps in Phulbani district of Orissa. These were preserved in 70% alcohol and immediately transferred to the laboratory. Various fractions in the collagen obtained from lens capsule of each lens sample were estimated. The salt-soluble and the acid-soluble collagens showed positive correlation with age. The insoluble and total capsular collagen increased with increasing age. The solubility percentage of collagen in salt and acid solutions decreased significantly with increasing age. The possible role of lens collagen in the development of cataract with increasing age is discussed in the background of cross-link theory of aging.en_US
dc.description.affiliationP.G. Department of Zoology, Berhampur University, India.en_US
dc.identifier.citationMishra G, Das GB, Behera HN. Possible role of lens collagen in cataractogenesis. Indian Journal of Ophthalmology. 1997 Dec; 45(4): 227-31en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/71516
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAging --physiologyen_US
dc.subject.meshCataract --etiologyen_US
dc.subject.meshCollagen --physiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLens Capsule, Crystalline --metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSolubilityen_US
dc.titlePossible role of lens collagen in cataractogenesis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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