Changes in erythrocyte contents of potassium, sodium and magnesium and Na, K-pump activity after the administration of potassium and magnesium salts.

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dc.contributor.authorSriboonlue, Poteen_US
dc.contributor.authorJaipakdee, Sudjaien_US
dc.contributor.authorJirakulsomchok, Dusiten_US
dc.contributor.authorMairiang, Eimornen_US
dc.contributor.authorTosukhowong, Piyaratanaen_US
dc.contributor.authorPrasongwatana, Vitoonen_US
dc.contributor.authorSavok, Sompongen_US
dc.date.accessioned2009-05-27T20:16:09Z
dc.date.available2009-05-27T20:16:09Z
dc.date.issued2004-12-13en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractLow potassium and magnesium status and decreased Na, K-pump activity is an endemic condition among rural Northeast Thais. The authors examined the effect of supplementing potassium and magnesium on erythrocyte potassium, sodium and magnesium content and on Na, K-pump activity. Rural Northeast Thai renal stone patients (62) were recruited, divided into four groups and supplemented for one month with potassium chloride (Group1, n = 16), potassium-sodium citrate (Group2, n = 15), chelated magnesium (Group 3, n =16) and potassium-magnesium citrate (Group 4, n =15) in order to achieve 40 mmol potassium, 10 mmol magnesium and 60 mmol citrate daily. After supplementation with potassium (Groups 1, 2 and 4), plasma potassium and Na, K-pump activity rose significantly in Groups 1, 2 and 4, but erythrocyte potassium rose only in Groups 2 and 4. When supplementing elemental magnesium (Groups 3 and 4), the chelated magnesium caused a significant increase in plasma potassium, erythrocyte potassium, sodium and magnesium without a significant increase in Na, K-pump activity. By contrast, potassium-magnesium citrate caused a significant increase in erythrocyte potassium and magnesium and Na, K-pump activity, but depressed erythrocyte sodium. These results suggest the forms of potassium and /or magnesium salts being supplemented should be considered because they affect erythrocyte potassium, sodium and magnesium content and Na, K-pump activity differently.en_US
dc.description.affiliationDepartment Biochemistry, Faculty Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.en_US
dc.identifier.citationSriboonlue P, Jaipakdee S, Jirakulsomchok D, Mairiang E, Tosukhowong P, Prasongwatana V, Savok S. Changes in erythrocyte contents of potassium, sodium and magnesium and Na, K-pump activity after the administration of potassium and magnesium salts. Journal of the Medical Association of Thailand. 2004 Dec; 87(12): 1506-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42682
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshErythrocytes --enzymologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Calculi --metabolismen_US
dc.subject.meshMagnesium --administration & dosageen_US
dc.subject.meshMaleen_US
dc.subject.meshPotassium --administration & dosageen_US
dc.subject.meshRural Populationen_US
dc.subject.meshSodium --blooden_US
dc.subject.meshSodium-Potassium-Exchanging ATPase --blooden_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleChanges in erythrocyte contents of potassium, sodium and magnesium and Na, K-pump activity after the administration of potassium and magnesium salts.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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