Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia.

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dc.contributor.authorKotru, Mrinalinien_US
dc.contributor.authorBatra, Madhuen_US
dc.contributor.authorGomber, Sunilen_US
dc.contributor.authorRusia, Ushaen_US
dc.date.accessioned2009-01-13en_US
dc.date.accessioned2009-05-29T12:45:42Z
dc.date.available2009-01-13en_US
dc.date.available2009-05-29T12:45:42Z
dc.date.issued2009-01-13en_US
dc.description.abstractThrombocytosis is commonly seen in reactive conditions and certain neoplastic states, such as chronic myeloproliferative disorders. It is rarely seen in acute leukemia. A 12-year-old girl with acute myeloblastic leukemia (FAB M2) in remission presented with pyoderma. Her hemogram revealed anemia (Hb-6.4g/dl), leucopenia (TLC - 1.2 x 109/L) and thrombocytosis (platelet count- 580 x 109/L). A peripheral blood film showed numerous abnormally large platelets with few atypical cells. The thrombocytosis subsided with the clearance of infection but atypical cells persisted. One month later, she relapsed. Cytogenetic analysis revealed variable results (trisomy 9 and deletion 3). This case has been presented because thrombocytosis is rare in AML and its appearance calls for a close follow-up.en_US
dc.description.affiliationDepartment of Pathology, University College of Medical Sciences and Associated Guru Teg Bahadur Hospital, New Delhi - 110 095, India. mrinalini.kotru@gmail.comen_US
dc.identifier.citationKotru M, Batra M, Gomber S, Rusia U. Transient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia. Indian Journal of Pathology & Microbiology. 2009 Jan-Mar; 52(1): 113-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74933
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAnemia --etiologyen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Myeloid, Acute --complicationsen_US
dc.subject.meshPyoderma --etiologyen_US
dc.subject.meshThrombocytosis --pathologyen_US
dc.titleTransient thrombocytosis with megathrombocytes in a case of acute myeloblastic leukemia.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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