Ki-67 labelling as a proliferation marker in pre-invasive squamous epithelial lesions of cervix.

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dc.contributor.authorPahuja, Sangeetaen_US
dc.contributor.authorChoudhury, Monishaen_US
dc.contributor.authorGupta, Ushaen_US
dc.date.accessioned2003-07-18en_US
dc.date.accessioned2009-05-29T11:54:48Z
dc.date.available2003-07-18en_US
dc.date.available2009-05-29T11:54:48Z
dc.date.issued2003-07-18en_US
dc.description.abstractStudy was conducted to evaluate proliferation in squamous intraepithelial lesions of cervix. 36 cases of cervical biopsies were chosen including unremarkable cervix, basal cell hyperplasia, cervical intraepithelial neoplasia (CIN I, CIN II, CIN III). Ki-67 immunostaining was performed by peroxidase-antiperoxidase method. Ki-67 labelling index in basal and parabasal layers of cervix showed progressive rise with increasing grade of lesion but may not be helpful in classification of individual lesion. Also extent of staining from the basement membrane increases with increasing grade. High basal Ki-67 reactivity might be of greater biological significance than surface differentiation.en_US
dc.description.affiliationDepartment of Pathology, Lady Hardinge Medical College, New Delhi. sangeetapahuja@indiatimes.comen_US
dc.identifier.citationPahuja S, Choudhury M, Gupta U. Ki-67 labelling as a proliferation marker in pre-invasive squamous epithelial lesions of cervix. Indian Journal of Pathology & Microbiology. 2003 Jul; 46(3): 402-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74028
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshCell Divisionen_US
dc.subject.meshCervical Intraepithelial Neoplasia --immunologyen_US
dc.subject.meshEpithelium --immunologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperplasiaen_US
dc.subject.meshKi-67 Antigen --metabolismen_US
dc.subject.meshTumor Markers, Biological --metabolismen_US
dc.subject.meshUterine Cervical Diseases --immunologyen_US
dc.subject.meshUterine Cervical Neoplasms --immunologyen_US
dc.titleKi-67 labelling as a proliferation marker in pre-invasive squamous epithelial lesions of cervix.en_US
dc.typeJournal Articleen_US
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