Real-time three-dimensional echocardiographic left heart parameters in healthy indian adults
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Date
2018-09
Journal Title
Journal ISSN
Volume Title
Publisher
Cardiological Society of India
Abstract
Objective
Cardiac chamber dimensions are race and anthropometry dependent. We determined the age and gender specific 3-Dimensional echocardiographic (3DE) reference values for dimensions and function of left ventricle (LV) and left atrium (LA) in normal Indian adults.
Methods
This single center prospective study enrolled 133 adult Indians free of heart disease and/or hypertensions, subjecting them to 3DE measurements of left atrial (LA) & left ventricular (LV) volumes, function and left ventricular mass (LVM). The higher limits of normal cut-offs were determined for these parameters and their dependency on age, gender and anthropometry were analyzed.
Results
The body surface area (BSA) corrected higher limit cut-offs were: 59.37 ml/m2 for LV end diastolic volume (59.19 ml/m2 and 59.61 ml/m2 for men and women, respectively; P = NS); 23.48 ml/m2 for LV end systolic volume (23.27 ml/m2 and 23.11 ml/m2 for men and women, P = NS). Mean LVEF was 64.79% ± 7.26 (62.99% ± 6.51 and 67.05% ± 7.58 in men and women, P = NS). Men had higher LVM than women (119.79 g±23.95 vs. 103.26 g±23.76, P < 0.001), this difference disappeared after BSA indexing. The higher limit cut-offs for normal LA volumes were 20.49 ml for minimum volume (21.18 ml and 19.46 ml for men and women, P = NS) and 39.76 ml for maximum volume (39.60 ml and 40.03 ml in men and women, P = NS). The parameters were smaller compared to western populations but the differences attenuated after BSA indexing.
Conclusions
The study reports normal 3DE parameters of size and function of left heart chambers in Indians.
Description
Keywords
Three-dimensional echocardiography, Left atrial volume, Left ventricular end diastolic volume, Left ventricular end systolic volume, Left atrial emptying fraction
Citation
Bhambhani Anupam, John Nelson, Mathew Amalu. Real-time three-dimensional echocardiographic left heart parameters in healthy indian adults. Indian Heart Journal. 2018 Sep; 70(5): 642-648