Incidence of catheter-related bloodstream infections after removal of peripherally inserted central catheters in preterm neonates

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dc.contributor.authorTomar, Rampal Singhen_US
dc.contributor.authorGupta, Ashish Kren_US
dc.contributor.authorKhan, I. D.en_US
dc.date.accessioned2020-09-24T07:46:57Z
dc.date.available2020-09-24T07:46:57Z
dc.date.issued2020-02
dc.description.abstractBackground: Peripherally inserted central catheter (PICC) have become essential for a safe and reliable long term venous access in all neonatal intensive care units (NICU) for providing long term intravenous fluids and medications. However, they associated with central line blood stream infections (CRBSI) infections and it is postulated that this risk is more on during their removal but the true incidence is not known. The objective was to evaluate the incidence and identify risk factors associated with CRBSI following the PICC removal in preterm neonates.Methods: This was a retrospective cohort study was done on <37 weeks premature neonates. Data included patient particulars, location of PICC placement, days of PICC, antibiotics and TPN through PICC, infections noted during or within 48 hours of PICC removal.Results: A total of 238 PICC removals in 215 neonates were analysed which did not show a significant difference in the prevalence of CRBSI within 48 hours of PICC removal. However, there was an increase in odds for sepsis following PICC removal in less than 29 weeks gestation and if it was not used for antibiotic infusion for more than 48 hours preceding its removal.Conclusions: This study does not support the use of prophylactic antibiotics during PICC removal in neonates as there was no increase in the incidence of CRBSI following PICC removal. However, they may have a role in very low gestation age, low birth weight infants who have not recently received antibiotics prior to PICC removal.en_US
dc.identifier.affiliationsDepartment of Pediatrics, Base Hospital Army College of Medical Sciences, Delhi Cant, Delhi, Indiaen_US
dc.identifier.affiliationsPaediatrician, Military Hospital, Secunderabad, Telangana, Indiaen_US
dc.identifier.affiliationsMicrobiologist, Command Hospital, Udhampur, Jammu and Kashmir, Indiaen_US
dc.identifier.citationTomar Rampal Singh, Gupta Ashish Kr, Khan I. D.. Incidence of catheter-related bloodstream infections after removal of peripherally inserted central catheters in preterm neonates. International Journal of Contemporary Pediatrics. 2020 Feb; 7(2): 282-286en_US
dc.identifier.issn2349-3283
dc.identifier.issn2349-3291
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/204427
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3291.ijcp20200018en_US
dc.subjectCatheter related bloodstream infectionen_US
dc.subjectNeonatal sepsisen_US
dc.subjectPeripheral inserted central venous catheters pretermen_US
dc.subjectProphylaxisen_US
dc.titleIncidence of catheter-related bloodstream infections after removal of peripherally inserted central catheters in preterm neonatesen_US
dc.typeJournal Articleen_US
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