Design and Characterization of Nanostructure Topical Gel of Betamethasone Dipropionate for Psoriasis.

Simple item page
dc.contributor.authorAlam, Md. Sarfaraz
dc.contributor.authorAli, Md. Sajid
dc.contributor.authorAlam, Nawazish
dc.contributor.authorAlam, Md. Intakhab
dc.contributor.authorAnwer, Tarique
dc.contributor.authorImam, Faisal
dc.contributor.authorAli, Md. Daud
dc.contributor.authorSiddiqui, Masoom Raza
dc.contributor.authorShamim, Md.
dc.date.accessioned2014-05-28T09:51:45Z
dc.date.available2014-05-28T09:51:45Z
dc.date.issued2012-10
dc.description.abstractPsoriasis is a chronic T lymphocyte mediated autoimmune inflammatory disorder that affects the skin, joints, and tendons. Betamethasone dipropionate (BD) has anti-inflammatory, immunosuppressive,and antiproliferative activity. The aim of this study was to investigate and evaluate a nanoemulsion topical gel of betamethasone dipropionate. For the preparation of nanoemulsion eucalyptus oil and babchi oil was taken. Nanomulsions were prepared by aqueous phase-titration method. Pseudoternary phase diagrams were constructed for the identification of nanoemulsion existence zones. Prepared nanoemulsions were subjected to different thermodynamic stability tests and characterized for droplet size, viscosity and refractive index. In vitro skin permeation of betamethasone dipropionate through rat abdominal skin was determined by the Franz diffusion cell. The prepared nanoemulsion gel is a potential vehicle for improved topical delivery of BD for better treatment of psoriasis.en_US
dc.identifier.citationAlam Md Sarfaraz, Ali Md Sajid, Alam Nawazish, Alam Md Intakhab, Anwer Tarique, Imam Faisal, Ali Md Daud, Siddiqui Masoom Raza, Shamim Md. Design and Characterization of Nanostructure Topical Gel of Betamethasone Dipropionate for Psoriasis. Journal of Applied Pharmaceutical Science. 2012 Oct; 2(10): 148-158.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/151435
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=684en_US
dc.subjectAnti-inflamatory effectsen_US
dc.subjectbetamethasone dipropionateen_US
dc.subjectpsoriasisen_US
dc.subjectnanoemulsionen_US
dc.subjecttransmission electron microscopyen_US
dc.subjecthistopathologyen_US
dc.titleDesign and Characterization of Nanostructure Topical Gel of Betamethasone Dipropionate for Psoriasis.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
japs2012v2n10p148.pdf
Size:
1000.06 KB
Format:
Adobe Portable Document Format
Description:
Research article
Download
Collections
Journal of Applied Pharmaceutical Science (JAPS)