Infective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital.

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dc.contributor.authorLertsapcharoen, Pornthepen_US
dc.contributor.authorKhongphatthanayothin, Apichaien_US
dc.contributor.authorChotivittayatarakorn, Pairojen_US
dc.contributor.authorThisyakorn, Chuleen_US
dc.contributor.authorPathmanand, Chotimaen_US
dc.contributor.authorSueblinvong, Virojen_US
dc.date.accessioned2009-05-27T18:00:01Z
dc.date.available2009-05-27T18:00:01Z
dc.date.issued2005-09-21en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVES: To review the clinical features and outcome of the pediatric patients diagnosed with infective endocarditis (IE) at King Chulalongkorn Memorial Hospital over an 18-year period. MATERIAL AND METHOD: From January 1987 to December 2004, 57 pediatric patients; 28 females and 29 males, age ranged from 2 months to 15 years, mean of 8.64 +/- 3.82 years, classified as "definite" IE according to the Duke criteria were reviewed. RESULTS: Of the 57 patients, 42 patients (74%) had underlying congenital heart diseases, 7 patients (12%) had underlying rheumatic heart disease, 8 patients (14%) had previously normal heart. Nine patients had history of previously palliative or corrective surgery. Blood cultures were positive in 26 patients (46%). Streptococci and staphylococci were the most commonly isolated organisms. Two-dimensional echocardiography demonstrated vegetations in 56 patients (98%). The location of the vegetations was in the right heart in 30 patients (54%) and in the left heart in 26 patients (46%). Complications occurred in 28 patients (49%). Common complications included congestive heart failure, cerebral emboli, septic shock, and mycotic aneurysm. The overall mortality was 11% (6 patients). By statistical analysis, vegetations in the left heart had a higher incidence of complication than that in the right heart. The vegetation size of > or =10 mm had a significant higher incidence of embolic events. CONCLUSION: The clinical features and outcomes of the present study have a similar pattern as the earlier studies. The rates of complications and mortality are still high.en_US
dc.description.affiliationDepartment of Pediatrics, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.en_US
dc.identifier.citationLertsapcharoen P, Khongphatthanayothin A, Chotivittayatarakorn P, Thisyakorn C, Pathmanand C, Sueblinvong V. Infective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital. Journal of the Medical Association of Thailand. 2005 Sep; 88 Suppl 4(): S12-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38246
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshEmbolization, Therapeuticen_US
dc.subject.meshEndocarditis, Bacterial --complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Defects, Congenital --complicationsen_US
dc.subject.meshHeart Failure --etiologyen_US
dc.subject.meshHospitalization --statistics & numerical dataen_US
dc.subject.meshHospitals, Urban --utilizationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshMedical Auditen_US
dc.subject.meshOutcome Assessment (Health Care)en_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshStaphylococcus aureus --isolation & purificationen_US
dc.subject.meshStreptococcus --isolation & purificationen_US
dc.subject.meshThailanden_US
dc.subject.meshTime Factorsen_US
dc.titleInfective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital.en_US
dc.typeJournal Articleen_US
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