Infective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital.
dc.contributor.author | Lertsapcharoen, Pornthep | en_US |
dc.contributor.author | Khongphatthanayothin, Apichai | en_US |
dc.contributor.author | Chotivittayatarakorn, Pairoj | en_US |
dc.contributor.author | Thisyakorn, Chule | en_US |
dc.contributor.author | Pathmanand, Chotima | en_US |
dc.contributor.author | Sueblinvong, Viroj | en_US |
dc.date.accessioned | 2009-05-27T18:00:01Z | |
dc.date.available | 2009-05-27T18:00:01Z | |
dc.date.issued | 2005-09-21 | en_US |
dc.description | Chotmaihet Thangphaet. | en_US |
dc.description.abstract | OBJECTIVES: To review the clinical features and outcome of the pediatric patients diagnosed with infective endocarditis (IE) at King Chulalongkorn Memorial Hospital over an 18-year period. MATERIAL AND METHOD: From January 1987 to December 2004, 57 pediatric patients; 28 females and 29 males, age ranged from 2 months to 15 years, mean of 8.64 +/- 3.82 years, classified as "definite" IE according to the Duke criteria were reviewed. RESULTS: Of the 57 patients, 42 patients (74%) had underlying congenital heart diseases, 7 patients (12%) had underlying rheumatic heart disease, 8 patients (14%) had previously normal heart. Nine patients had history of previously palliative or corrective surgery. Blood cultures were positive in 26 patients (46%). Streptococci and staphylococci were the most commonly isolated organisms. Two-dimensional echocardiography demonstrated vegetations in 56 patients (98%). The location of the vegetations was in the right heart in 30 patients (54%) and in the left heart in 26 patients (46%). Complications occurred in 28 patients (49%). Common complications included congestive heart failure, cerebral emboli, septic shock, and mycotic aneurysm. The overall mortality was 11% (6 patients). By statistical analysis, vegetations in the left heart had a higher incidence of complication than that in the right heart. The vegetation size of > or =10 mm had a significant higher incidence of embolic events. CONCLUSION: The clinical features and outcomes of the present study have a similar pattern as the earlier studies. The rates of complications and mortality are still high. | en_US |
dc.description.affiliation | Department of Pediatrics, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand. | en_US |
dc.identifier.citation | Lertsapcharoen P, Khongphatthanayothin A, Chotivittayatarakorn P, Thisyakorn C, Pathmanand C, Sueblinvong V. Infective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital. Journal of the Medical Association of Thailand. 2005 Sep; 88 Suppl 4(): S12-6 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/38246 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.mat.or.th/journal/all.php | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Child | en_US |
dc.subject.mesh | Child, Preschool | en_US |
dc.subject.mesh | Embolization, Therapeutic | en_US |
dc.subject.mesh | Endocarditis, Bacterial --complications | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Heart Defects, Congenital --complications | en_US |
dc.subject.mesh | Heart Failure --etiology | en_US |
dc.subject.mesh | Hospitalization --statistics & numerical data | en_US |
dc.subject.mesh | Hospitals, Urban --utilization | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Infant | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Medical Audit | en_US |
dc.subject.mesh | Outcome Assessment (Health Care) | en_US |
dc.subject.mesh | Retrospective Studies | en_US |
dc.subject.mesh | Risk Factors | en_US |
dc.subject.mesh | Staphylococcus aureus --isolation & purification | en_US |
dc.subject.mesh | Streptococcus --isolation & purification | en_US |
dc.subject.mesh | Thailand | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Infective endocarditis in pediatric patients: an eighteen-year experience from King Chulalongkorn Memorial Hospital. | en_US |
dc.type | Journal Article | en_US |
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