HLA-B5 and B21 antigens in aortoarteritis.

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dc.contributor.authorRose, Sen_US
dc.contributor.authorMehra, N Ken_US
dc.contributor.authorKumar, Ren_US
dc.contributor.authorVaidya, M Cen_US
dc.date.accessioned1991-01-01en_US
dc.date.accessioned2009-05-30T10:30:35Z
dc.date.available1991-01-01en_US
dc.date.available2009-05-30T10:30:35Z
dc.date.issued1991-01-01en_US
dc.description.abstractThe distribution of class I HLA antigens (HLA-A, B) were determined in 50 patients of Aortoarteritis in an Indian population. This included 29 females and 21 males. The difference in antigen frequency was observed between patients and controls with reference to HLA-A19, B5 and B21 antigens. A decreased frequency of HLA-A19 was observed in the patients as compared to controls (14% vs 33.25%, X2 = 6.81, P less than 0.025). Of the B locus antigens, an increased frequency of HLA B5 was observed in the patients as compared to controls (48% vs 29.5%, X2 = 6.2, P less than 0.025). HLA-B21 was also increased in the patients as compared to the controls (18% vs 6.5%, X2 = 6.67, P less than 0.025). These data suggest the involvement of genetic factor (s) in the aetiopathogenesis of this disease. Further, the observations indicate that HLA-B5 and B21 may be associated with Aortoarteritis.en_US
dc.description.affiliationDepartment of Anatomy, All India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationRose S, Mehra NK, Kumar R, Vaidya MC. HLA-B5 and B21 antigens in aortoarteritis. Indian Journal of Pediatrics. 1991 Jan-Feb; 58(1): 85-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/78719
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAortitis --geneticsen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHLA-A Antigens --analysisen_US
dc.subject.meshHLA-B Antigens --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.titleHLA-B5 and B21 antigens in aortoarteritis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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