Multicystic Dysplastic Kidney: A Retrospective Study.
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Date
2014-08
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Abstract
Objective: To report the renal structural and functional anomalies in children with multicystic
dysplastic kidneys. Methods: Retrospective descriptive analysis of 47 children with
multicystic dysplastic kidney seen in a pediatric nephrology unit over a period of 6 years.
Results: Antenatal diagnosis of multicystic dysplastic kidney was made in 34 (72.3%)
patients. On follow up of 31 children for more than 12 months, 21 (68%) had involution, 4
[13%] had non-regression, and 4 (13%) were nephrectomized. Vesico-ureteric reflux (n=13;
28%) was the commonest renal abnormality. The serum creatinine values were higher
(P=0.006) in children with contralateral reflux. Sub-nephrotic proteinuria was noted in 9 (29%)
and was significantly associated with complete involution (P=<0.023). None of the patients
developed hypertension and 2 (6.4%) had renal failure. Conclusion: Close nephrological
follow-up is needed in children with multicystic dysplasia of kidneys.
Description
Keywords
Hyperfiltration injury, Multicystic dysplastic kidney, Proteinuria
Citation
Sharada Sathish, Vijayakumar Mahalingam, Nageswaran Prahlad, Ekambaram Sudha, Udani Amish. Multicystic Dysplastic Kidney: A Retrospective Study. Indian Pediatrics. 2014 Aug; 51(8): 641-643.