Cloning and sequencing of α-2u globulin of rat preputial gland to assess its longevity in the context of developing an effective rodent trap

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dc.contributor.authorSilambarasan, Ven_US
dc.contributor.authorGayathiri, Sen_US
dc.contributor.authorDeepalakshmi, Gen_US
dc.contributor.authorBanu, M Shahithaen_US
dc.contributor.authorNithya, Ven_US
dc.contributor.authorArchunan, Gen_US
dc.date.accessioned2020-01-02T06:23:24Z
dc.date.available2020-01-02T06:23:24Z
dc.date.issued2019-12
dc.description.abstractα-2u globulin, a pheromone binding protein found majorly in the preputial gland, was reported to involve in chemo-communication of rats. The biosynthesis of this pheromone binding protein is under complex multihormonal control and its regulation takes place at transcription level. Assessing and increasing the longevity of this protein may retain the volatility of pheromone. So far nearly 20 isoforms of α-2u globulin in rat have been studied. The present study was aimed to extend the longevity of pheromone compound by cloning and sequencing of the mRNA which codes for α-2u globulin in the preputial gland of Rattus novergicus. Unexpectedly, this study resulted in a new isoform, which is similar in function with α-2u globulin protein with some different exons removed. Further analysis with this isoform may pave a way for rodent pest management.en_US
dc.identifier.affiliationsPheromone Technology Lab, Department of Animal Science, Bharathidasan University, Tiruchirappalli – 620 024, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Animal Health and management, Alagappa University, Karaikudi- 630 003, Tamil Nadu, Indiaen_US
dc.identifier.citationSilambarasan V, Gayathiri S, Deepalakshmi G, Banu M Shahitha, Nithya V, Archunan G. Cloning and sequencing of α-2u globulin of rat preputial gland to assess its longevity in the context of developing an effective rodent trap. Indian Journal of Biochemistry and Biophysics. 2019 Dec; 56(6): 433-438en_US
dc.identifier.issn0975-0959
dc.identifier.issn0301-1208
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190073
dc.languageenen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.relation.issuenumber6en_US
dc.relation.volume56en_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/52173en_US
dc.titleCloning and sequencing of α-2u globulin of rat preputial gland to assess its longevity in the context of developing an effective rodent trapen_US
dc.typeJournal Articleen_US
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