Prevention and control of thalassemia in Ramathibodi Hospital, Thailand.

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dc.contributor.authorJaovisidha, Aen_US
dc.contributor.authorAjjimarkorn, Sen_US
dc.contributor.authorPanburana, Pen_US
dc.contributor.authorSomboonsub, Oen_US
dc.contributor.authorHerabutya, Yen_US
dc.contributor.authorRungsiprakarn, Ren_US
dc.date.accessioned2009-05-27T14:53:50Z
dc.date.available2009-05-27T14:53:50Z
dc.date.issued2000-09-06en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractEight thousand seven hundred and thirty-six pregnant women were screened for thalassemia and hemoglobinopathies by mean corpuscular volume less than 80 femtolitres (fl). Three thousand six hundred and seventy women (42%) were MCV less than 80 fl. In this group there were 2,390 women (70%) who had positive Hb typing by high performance liquid chromatography (HPLC) such as beta-thalassemia major, beta-thalassemia hemoglobin E disease, beta-thalassemia trait, heterozygous and homozygous hemoglobin E, alpha-thalassemia-1 trait and hemoglobin H disease and 77% of their partners came and had hemoglobin typing done. Seventy-five couples at risk for having severely affected thalassemia fetuses were detected from this screening program. Prenatal diagnosis was performed in 58 couples (77.3%). Eight affected fetuses were detected. All pregnancies with affected fetuses except one with beta-thalassemia/HbE were terminated. There were 3 fetal losses (6%) as the result of prenatal diagnosis procedure.en_US
dc.description.affiliationDepartment of Obstetrics and Gynecology, Ramathibodi Hospital, Bangkok, Thailand.en_US
dc.identifier.citationJaovisidha A, Ajjimarkorn S, Panburana P, Somboonsub O, Herabutya Y, Rungsiprakarn R. Prevention and control of thalassemia in Ramathibodi Hospital, Thailand. The Southeast Asian Journal of Tropical Medicine and Public Health. 2000 Sep; 31(3): 561-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/31377
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2000_31_3/28-2478.pdfen_US
dc.subject.meshChromatography, High Pressure Liquiden_US
dc.subject.meshDiagnostic Tests, Routineen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeterozygoteen_US
dc.subject.meshHomozygoteen_US
dc.subject.meshHospitals, Urbanen_US
dc.subject.meshHumansen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPrenatal Diagnosisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshThalassemia --diagnosisen_US
dc.titlePrevention and control of thalassemia in Ramathibodi Hospital, Thailand.en_US
dc.typeJournal Articleen_US
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