Myeloma coexisting with jejunal light chain amyloidosis

Simple item page
dc.contributor.authorMarimuthu, Aishwarya K.en_US
dc.contributor.authorRamkumar, Purnimaen_US
dc.contributor.authorAbdulsalam, Mohammed S.en_US
dc.contributor.authorPandurangan, Prabuen_US
dc.contributor.authorJameel, Jainudeen Khalander Abdulen_US
dc.contributor.authorMenon, Mayaen_US
dc.date.accessioned2020-11-18T10:02:29Z
dc.date.available2020-11-18T10:02:29Z
dc.date.issued2020-10
dc.description.abstractAmyloid Light chain (AL) amyloidosis is a rare disease, which is seen in approximately one-tenth of patients with multiple myeloma. We report a 52 years old male, who presented with complaints of anorexia and weight loss. He was diagnosed to have multiple myeloma-international staging score (ISS) Stage 3 and was started on VTD (Bortezomib, Thalidomide, and Dexamethasone) chemotherapy. Within 2 weeks of therapy, he had abdominal symptoms like abdominal pain, loose stools, vomiting and hematochezia. Imaging showed dilated proximal bowel loops with fluid filled contents and prominent vessels in rectum. Emergency surgical exploration revealed thickened proximal jejunum with blood clots in the lumen. Resection of proximal jejunum was done. Histopathological examination of resected specimen was suggestive of AL amyloidosis. Post-surgical resection of jejunum, patient had initial improvement followed by deterioration. He was discharged against medical advice as per relative’s request. Hence an index of clinical suspicion of amyloidosis must been present in all Multiple myeloma patients.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Apollo Main Hospital, Greams Road, Chennai, India.en_US
dc.identifier.affiliationsDepartment of Internal Medicine/Hematology, Apollo Main Hospital, Greams Road, Chennai, India.en_US
dc.identifier.affiliationsDepartment of Hematology, Apollo Main Hospital, Greams Road, Chennai, India.en_US
dc.identifier.affiliationsDepartment of Surgical Gastroenterology, Apollo Main Hospital, Greams Road, Chennai, India.en_US
dc.identifier.affiliationsDepartment of Pathology, Apollo Main Hospital, Greams Road, Chennai, India.en_US
dc.identifier.citationMarimuthu Aishwarya K., Ramkumar Purnima, Abdulsalam Mohammed S., Pandurangan Prabu, Jameel Jainudeen Khalander Abdul, Menon Maya. Myeloma coexisting with jejunal light chain amyloidosis. International Journal of Research in Medical Sciences. 2020 Oct; 8(10): 3738-3741en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212556
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber10en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20204264en_US
dc.subjectJejunal amyloidosisen_US
dc.subjectMyelomaen_US
dc.subjectHematocheziaen_US
dc.titleMyeloma coexisting with jejunal light chain amyloidosisen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijrms2020v8n10p3738.pdf
Size:
366.99 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences