Primary amoebic meningoencephalitis due to Naegleria fowleri.

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dc.contributor.authorKaushal, Ven_US
dc.contributor.authorChhina, D Ken_US
dc.contributor.authorRam, Shobhaen_US
dc.contributor.authorSingh, Gen_US
dc.contributor.authorKaushal, R Ken_US
dc.contributor.authorKumar, Ren_US
dc.date.accessioned2008-06-01en_US
dc.date.accessioned2009-05-31T03:50:38Z
dc.date.available2008-06-01en_US
dc.date.available2009-05-31T03:50:38Z
dc.date.issued2008-06-01en_US
dc.description11 references.en_US
dc.description.abstractPrimary amoebic meningoencephalitis (PAM) due to Naegleria fowleri was detected in a 36-year-old, Indian countryman who had a history of taking bath in the village pond. He was admitted in a semi comatosed condition with severe frontal headache, neck stiffness, intermittent fever, nausea, vomiting, left hemiparesis and seizures. Computerized tomography (CT) scan of brain showed a soft tissue non-enhancing mass with erosion of sphenoid sinus. However CSF findings showed no fungal or bacterial pathogen. Trophozoites of Naegleria fowleri were detected in the direct microscopic examination of CSF and these were grown in culture on non-nutrient agar. The patient was put on amphotericin-B, rifampicin and ceftazidime but his condition deteriorated and was taken home by his relatives in a moribund condition against medical advice and subsequently died. A literature review of 7 previous reports of PAM in India is also presented. Four of theses eight cases were non lethal. The mean age was 13.06 years with male: female ratio of 7:1. History of contact with water was present in four cases. Trophozoites could be identified in all 8 cases in this series.en_US
dc.description.affiliationDepartment of Microbiology; Dayanand Medical College and Hospital (DMC & H), Ludhiana, Punjab, India.en_US
dc.identifier.citationKaushal V, Chhina DK, Ram S, Singh G, Kaushal RK, Kumar R. Primary amoebic meningoencephalitis due to Naegleria fowleri. Journal of the Association of Physicians of India. 2008 Jun; 56(): 459-62en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/94247
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAmebiasis --diagnosisen_US
dc.subject.meshAmphotericin B --therapeutic useen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCeftazidime --therapeutic useen_US
dc.subject.meshCentral Nervous System Protozoal Infections --diagnosisen_US
dc.subject.meshCerebrospinal Fluid --parasitologyen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshNaegleria fowleri --isolation & purificationen_US
dc.subject.meshRifampin --therapeutic useen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.subject.meshTreatment Refusalen_US
dc.titlePrimary amoebic meningoencephalitis due to Naegleria fowleri.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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