Cognitive functions in stable schizophrenia & euthymic state of bipolar disorder.

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dc.contributor.authorTrivedi, J Ken_US
dc.contributor.authorGoel, Dishanteren_US
dc.contributor.authorSharma, Sachinen_US
dc.contributor.authorSingh, A Pen_US
dc.contributor.authorSinha, P Ken_US
dc.contributor.authorTandon, Rajulen_US
dc.date.accessioned2007-11-28en_US
dc.date.accessioned2009-05-27T07:54:18Z
dc.date.available2007-11-28en_US
dc.date.available2009-05-27T07:54:18Z
dc.date.issued2007-11-28en_US
dc.description.abstractBACKGROUND & OBJECTIVE: Some cognitive deficits in schizophrenia and bipolar disorders persist after the subsidence of active symptoms. We carried out this study to assess and compare the cognitive functioning of patients with stable schizophrenia and bipolar disorder. METHODS: Fifteen each of stable maintained schizophrenic patients and euthymic bipolar-I patients attending outpatient clinic in a tertiary care psychiatric hospital in north India were included in the study as also equal number of age and education matched control subjects. Cognitive assessments were done using Wisconsin's Card Sorting Test (WCST), Spatial Working Memory Test (SWMT) and Continuous Performance Test (CPT). RESULTS: Stable schizophrenia patients performed poorly on all the neurocognitive parameters as compared to both controls and bipolar euthymic patients. Euthymic bipolar patients showed significant difference on executive functions with normal controls. Patterns of cognitive disturbances in tasks of executive function are similar in both groups but are quantitatively more marked in schizophrenia. INTERPRETATION & CONCLUSION: Our results showed that stable schizophrenia patients performed significantly worse on cognitive measures than patients of euthymic bipolar disorder which was consistent with their poorer functional outcome. The results further indicated that stable schizophrenia and euthymic bipolar disorders may be distinguished qualitatively in neuropsychological terms with different profiles of cognitive impairment.en_US
dc.description.affiliationDepartment of Psychiatry, King George's Medical University, Lucknow, India. jktrivedi@hotmail.comen_US
dc.identifier.citationTrivedi JK, Goel D, Sharma S, Singh AP, Sinha PK, Tandon R. Cognitive functions in stable schizophrenia & euthymic state of bipolar disorder. Indian Journal of Medical Research. 2007 Nov; 126(5): 433-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/22513
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBipolar Disorder --physiopathologyen_US
dc.subject.meshCognition --physiologyen_US
dc.subject.meshCognition Disorders --physiopathologyen_US
dc.subject.meshHospitals, Psychiatricen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshIntelligenceen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshSchizophrenia --physiopathologyen_US
dc.subject.meshSchizophrenic Psychologyen_US
dc.titleCognitive functions in stable schizophrenia & euthymic state of bipolar disorder.en_US
dc.typeJournal Articleen_US
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