Acute toxicity of concurrent chemoradiation with weekly cisplatin in cervical cancer patients
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2011-01-24
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Journal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์
Abstract
Between January 2009 and August 2009, 19 consecutively previously untreated patients with invasivecervical carcinoma had completed concurrent chemoradiation treatment at Ubonratchathani cancercenter. Clinical stage were IB2 : 2 IIA: 4 IIB : 10 IIIB : 3 . A total of 83 cycles of cisplatin were administeredto the patients ,with a median of 4 cycles (range, 3 - 6 ). Severe hematological occurred in 3 patients (16%)No severe gastrointestinal toxicity occurred, only grade 2 in 1 patients (5 %). The grades of hematologicaland gastrointestinal toxicity were less than other studies. These results may be from lesser numbers ofpatients given cisplatin 6 cycles or more.
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Journal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์; Vol.17 No.1 January-June 2011; 6