Chalcones bearing N, O, and S-heterocycles: Recent notes on their biological significances

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dc.contributor.authorArdiansah, Bayuen_US
dc.date.accessioned2020-10-16T08:55:42Z
dc.date.available2020-10-16T08:55:42Z
dc.date.issued2019-08
dc.description.abstractBecause of its relatively easy synthesis, chalcone skeleton has been as a point of interest for organic and medicinalchemists from research groups worldwide. Chalcone scaffold constitutes the core of some interesting biologicallyactive natural products. Chalcone derivatives are among feasible potent active agents, such as anticancer, antibacterial,antifungal, antileishmanial, antimalarial, and antiviral. Due to the knowledge of heterocyclic chemistry, recentlychalcones bearing heterocyclic moieties have been synthesized and biologically investigated for specific target ofdiseases. The current review focuses on the latest application of chalcones integrated with N, O, and S-heterocyclicsystem and their wide spectrum of biological performance during 10 years (2010–2019). The results reported inthe review indicate that many chalcone-heterocycle hybrids may be useful as future drug candidates due to theircomparable or higher activity than that of the standards.en_US
dc.identifier.affiliationsDepartment of Chemistry, FMIPA, Universitas Indonesia, Depok, 16424, Indonesia.en_US
dc.identifier.citationArdiansah Bayu. Chalcones bearing N, O, and S-heterocycles: Recent notes on their biological significances. Journal of Applied Pharmaceutical Science. 2019 Aug; 2019 Aug: 117-129en_US
dc.identifier.issn2231-3354
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/210433
dc.languageenen_US
dc.publisherOpen Science Publishers LLPen_US
dc.relation.issuenumber8en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.7324/JAPS.2019.90816en_US
dc.subjectChalconesen_US
dc.subjectheterocyclicen_US
dc.subjectNen_US
dc.subjectOen_US
dc.subjectS-heteroaromaticen_US
dc.subjectbiological activityen_US
dc.subjectpotent drugs.en_US
dc.titleChalcones bearing N, O, and S-heterocycles: Recent notes on their biological significancesen_US
dc.typeJournal Articleen_US
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