Dead space ventilation in volume controlled versus pressure controlled mode of mechanical ventilation.

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dc.contributor.authorWathanasormsiri, Apassornen_US
dc.contributor.authorPreutthipan, Aroonwanen_US
dc.contributor.authorChantarojanasiri, Teerachaien_US
dc.contributor.authorSuwanjutha, Subhareeen_US
dc.date.accessioned2009-05-27T20:26:11Z
dc.date.available2009-05-27T20:26:11Z
dc.date.issued2002-11-29en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractDead space ventilation (VD) is one of the important measurements that indicates the ventilatory efficiency of a patient who requires mechanical ventilation. However, VD is not constant and can change according to the pathology in the lungs, ventilatory patterns, perfusion and ventilation-perfusion matching. The objective of this study was to measure and compare the dead space in pediatric patients who were using pressure controlled and volume controlled modes of mechanical ventilatory by measuring the difference between arterial PCO2 and end-tidal PCO2 [P(a-ET)CO2]. From November 1996 to March 1997, 12 patients who were admitted to the pediatric intensive care unit and needed ventilator support for various reasons, were enrolled in the study. Their ages ranged from 2 to 15 years. The mechanical ventilator (Benett 7200 or Servo 900C) setting during VD measurement i.e. tidal volume, inspiratory time and positive end expiratory pressure were kept constant between changing from pressure controlled to volume controlled mode or vice versa for twenty minutes in order to allow adequate time for equilibration. The P(a-ET)CO2 between volume controlled and pressure controlled mode were 3.1 and 2.6 torr (p = 0.5) and peak inspiratory pressure were 20.0 and 17.3 torr (p = 0.01), respectively; whereas mean airway pressure, PaO2, O2 saturation and heart rate revealed no significant difference between these two modes. The authors concluded that VD in pressure controlled mode from the present study was not significantly different from VD when using volume controlled mode of mechanical ventilation in the same patient. However, VD will change according to the pathophysiologic change in respiratory system and can be used for monitoring of ventilatory pattern of patients in the pediatric intensive care unit.en_US
dc.description.affiliationDepartment of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.en_US
dc.identifier.citationWathanasormsiri A, Preutthipan A, Chantarojanasiri T, Suwanjutha S. Dead space ventilation in volume controlled versus pressure controlled mode of mechanical ventilation. Journal of the Medical Association of Thailand. 2002 Nov; 85 Suppl 4(): S1207-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42994
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshBlood Gas Analysisen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPositive-Pressure Respirationen_US
dc.subject.meshRespiration Disorders --physiopathologyen_US
dc.subject.meshRespiratory Dead Space --physiologyen_US
dc.subject.meshTidal Volume --physiologyen_US
dc.titleDead space ventilation in volume controlled versus pressure controlled mode of mechanical ventilation.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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