Stevens-Johnson syndrome induced by carbamazepine andamitriptyline in diabetic patient: a case report

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dc.contributor.authorPutra, Agus Dody Pranata Suadien_US
dc.contributor.authorSuryana, Ketuten_US
dc.contributor.authorWulandari, Dewi Caturen_US
dc.contributor.authorPriyadarshini, Ida Ayu Uttarien_US
dc.date.accessioned2023-08-28T06:36:04Z
dc.date.available2023-08-28T06:36:04Z
dc.date.issued2022-08
dc.description.abstractStevens-Johnson syndrome (SJS) is systemic immune reactions (type IV hypersensitivity) that are usually present by blistering and erosions of skin and mucous membranes with involvement of multiple organ systems. The incidence of SJS is rare, with the common comorbidities are diabetes mellitus, epilepsy, hypertension, and stroke. This condition is associated with systemic proinflammatory state. Diabetes mellitus is a metabolic disorder that is characterized by abnormally elevated levels of blood glucose due to glucose intolerance, hyperglycemia, and impaired insulin secretion. Nowadays, pathogenesis of diabetes is considered to be dysregulation of immune factors that are recognized as important etiological components in the development of insulin resistance. We report a case of a 30-years-old man with fever and sore throat, who had type 2 diabetes mellitus (T2DM) and used carbamazepine and amitriptyline for diabetic neuropathy, then followed by redness and blistering on his lips, palates, face, and trunk which subsequently diagnosed with SJS.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, WangayaRegional Hospital, Denpasar, Bali, Indonesiaen_US
dc.identifier.citationPutra Agus Dody Pranata Suadi, Suryana Ketut, Wulandari Dewi Catur, Priyadarshini Ida Ayu Uttari. Stevens-Johnson syndrome induced by carbamazepine andamitriptyline in diabetic patient: a case report. International Journal of Advances in Medicine. 2022 Aug; 9(8): 875-878en_US
dc.identifier.issn2349-3933
dc.identifier.issn2349-3925
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/225862
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber8en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20221845en_US
dc.subjectSteven-Johnson syndromeen_US
dc.subjectDiabetes mellitusen_US
dc.subjectImmune reactionsen_US
dc.titleStevens-Johnson syndrome induced by carbamazepine andamitriptyline in diabetic patient: a case reporten_US
dc.typeJournal Articleen_US
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