Granular cell ameloblastoma: A rare and unique variant

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dc.contributor.authorSukumaran, Renuen_US
dc.contributor.authorSomanathan, Tharaen_US
dc.contributor.authorSen, Anithaen_US
dc.date.accessioned2023-08-09T06:15:49Z
dc.date.available2023-08-09T06:15:49Z
dc.date.issued2022-11
dc.description.abstractAmeloblastoma is a slow-growing and locally invasive epithelial odontogenic tumor of the jaw that runs a benign course in most cases. Granular cell ameloblastoma is a rare subtype of ameloblastoma, showing the granular transformation of its cytoplasm. It is considered as an aggressive variant of ameloblastoma. Herein, we report the case of a 34-year-old male patient who presented with a swelling in the left cheek for a 1-year duration with a recent rapid increase in size. Examination showed a 4 � 3 cm growth involving the left buccal mucosa and retromolar area. Imaging studies showed expansile lytic lesion mandible. Biopsy revealed neoplasm with odontogenic epithelial islands showing peripheral palisading of tall columnar cells with reversal of polarity and the center of the islands showing stellate reticulum-like cells which were markedly replaced by granular cells. Granular cells can appear in various odontogenic and non-odontogenic tumors. When there is extensive granular cell change in ameloblastoma, it should be differentiated from other oral lesions with granular cells including granular cell odontogenic tumor, granular cell tumor, and congenital epulis.en_US
dc.identifier.affiliationsAssociate Professoren_US
dc.identifier.affiliationsAdditional Professor, Department of Pathologyen_US
dc.identifier.affiliationsAssistant Professor, Department of Imageology, Regional Cancer Centre, Thiruvananthapuram, Kerala, Indiaen_US
dc.identifier.citationSukumaran Renu, Somanathan Thara, Sen Anitha. Granular cell ameloblastoma: A rare and unique variant. Indian Journal of Case Reports. 2022 Nov; 8(11): 360-362en_US
dc.identifier.issn2454-1303
dc.identifier.issn2454-129X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222259
dc.languageenen_US
dc.publisherMansa STM Publishersen_US
dc.relation.issuenumber11en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.32677/ijcr.v8i11.3359en_US
dc.subjectAggressive varianten_US
dc.subjectGranular cell ameloblastomaen_US
dc.subjectOdontogenic tumoren_US
dc.titleGranular cell ameloblastoma: A rare and unique varianten_US
dc.typeJournal Articleen_US
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