Prevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive women

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dc.contributor.authorMalik, Sunitaen_US
dc.contributor.authorKumari, Supritien_US
dc.contributor.authorGaikwad, Harsha S.en_US
dc.contributor.authorMishra, Archanaen_US
dc.contributor.authorBharadwaj, Mausumien_US
dc.date.accessioned2020-10-16T07:58:46Z
dc.date.available2020-10-16T07:58:46Z
dc.date.issued2019-09
dc.description.abstractBackground: The relationship among HIV, HPV, and development of CIN is complex and incompletely understood. Present study is undertaken to find out the prevalence and relationship of abnormal cervical cytology and HPV infection in HIV positive women.Methods: This was a cross-sectional, case control study conducted on 95 HIV seropositive and 95 seronegative women. Specimen was collected from the cervix for HPV DNA testing, subtyping and cytology.Results: HPV DNA positivity was higher in seropositive group (18.6% vs. 7.4%). Premalignant conditions were found only in seropositive group. At CD4 count <249 HPV DNA positivity was 53%, at 250-499 the percentage of HPV DNA positivity was 31% and at >500 HPV DNA positivity was 19%.Conclusions: Prevalence of abnormal cytology and HPV DNA positivity is higher amongst HIV positive women and there is an association between HPV DNA positivity with lower CD4 counts.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, Indiaen_US
dc.identifier.affiliationsDivision of Molecular Genetics and Biochemistry, Institute of Cytology and Preventive Oncology (ICMR), Noida, Uttar Pradesh, Indiaen_US
dc.identifier.citationMalik Sunita, Kumari Supriti, Gaikwad Harsha S., Mishra Archana, Bharadwaj Mausumi. Prevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive women. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Sep; 8(9): 3649-3653en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207025
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20193791en_US
dc.subjectAbnormal cytologyen_US
dc.subjectCervixen_US
dc.subjectHIVen_US
dc.subjectHPV infectionen_US
dc.titlePrevalence of abnormal cervical cytology and HPV DNA positivity among HIV positive womenen_US
dc.typeJournal Articleen_US
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