Early cognitive decline and its assessment in idiopathic Parkinson disease and its correlation with duration of illness

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dc.contributor.authorGupta, Ajesh C.en_US
dc.contributor.authorShukla, Poojaen_US
dc.contributor.authorGiri, Richaen_US
dc.date.accessioned2023-08-28T06:35:59Z
dc.date.available2023-08-28T06:35:59Z
dc.date.issued2022-05
dc.description.abstractBackground:Parkinson disease(PD)is one of the most common age-related brain disorders, with cardinal symptoms rigidity, bradykinesia, resting tremor and postural instability. These aredopamine-related motor symptoms.PD is increasingly recognized as heterogeneous multisystem disorder involving other neurotransmitter associated with nonmotor symptoms. In whichcognitive decline is the most common and important NMS. cognitive decline in PD makes profound effect on patient quality of life and imposes significant burden on the caregiver.Methods:Hospital based cross sectional study conducted among 52 patients of idiopathic Parkinson disease, 61 to 80 years of age (fulfilling UKPDS brain bank criteria) at GSVM medical college, Kanpur during February 2020 to October2021 using SCOPA COG scale.Results:Using SCOPA COG score in 52 patients,17 (33%) patients foundwith declined cognition There was weak negative correlation betweentotal score and duration of illness(p=0.091), weak negative correlation between executive function (assessed by dice) and duration of illness (p=0.047)and a moderate negative correlationbetween visuospatial function (assessed by assembling pattern) and duration of illness (p=0.003).Conclusions:Significant cognitive decline found with increase in duration of illness in terms of visuospatial function.en_US
dc.identifier.affiliationsDepartment of Medicine, GSVM Medical College,Kanpur,Uttar Pradesh, Indiaen_US
dc.identifier.citationGupta Ajesh C., Shukla Pooja, Giri Richa. Early cognitive decline and its assessment in idiopathic Parkinson disease and its correlation with duration of illness. International Journal of Advances in Medicine. 2022 May; 9(5): 587-590en_US
dc.identifier.issn2349-3933
dc.identifier.issn2349-3925
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/225797
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber5en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20221094en_US
dc.subjectParkinson diseaseen_US
dc.subjectCognitive declineen_US
dc.subjectSCOPA COGen_US
dc.titleEarly cognitive decline and its assessment in idiopathic Parkinson disease and its correlation with duration of illnessen_US
dc.typeJournal Articleen_US
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