Harnessing nanotechnology for enhanced epilepsy management

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dc.contributor.authorManasa, V.en_US
dc.contributor.authorRuby, J. Joysaen_US
dc.contributor.authorGogoi, Himadri Priyaen_US
dc.contributor.authorVignesh, S.en_US
dc.contributor.authorAnjaneya, P. H.en_US
dc.contributor.authorAkhilen_US
dc.date.accessioned2025-05-12T11:41:42Z
dc.date.available2025-05-12T11:41:42Z
dc.date.issued2024-12
dc.description.abstractEpilepsy, a condition characterized by unprovoked, recurrent seizures, currently has no cure, with treatments ranging from medications to treatment modalities such as antiepileptic drugs (AEDs) and vagus nerve stimulation, as well as ketogenic diet and surgical procedures. Recent advancements in nanotechnology have introduced groundbreaking approaches to epilepsy treatment, including targeted drug delivery, diagnostics, and therapeutic interventions. Nanocarrier systems—such as nanoparticles, micelles, and liposomes—enhance drug specificity for brain delivery, improving the therapeutic efficacy and reducing off-target toxicity. New developments in nanocarrier systems for AEDs, including phenytoin, phenobarbital, carbamazepine, and valproate, demonstrate increased brain penetration, solubility, and controlled drug release, offering promising benefits in epilepsy management. Nanotechnology also advances diagnostic capabilities with nano-sensitive devices such as enhanced electroencephalography and biomarker technologies, enabling more personalized monitoring and treatment. Prospects include nanodroplet drug delivery, neural repair with nanomaterials, and highly individualized epilepsy therapies. These innovations could significantly improve traditional treatments, patient outcomes, and quality of life, underscoring the importance of collaboration among healthcare providers, scientists, and technologists to maximize their potential. Efforts have been made to present epilepsy and its management graphically.en_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, Indiaen_US
dc.identifier.citationManasa V., Ruby J. Joysa, Gogoi Himadri Priya, Vignesh S., Anjaneya P. H., Akhil. Harnessing nanotechnology for enhanced epilepsy management. MGM Journal of Medical Sciences. 2024 Dec; 11(4): 782-793en_US
dc.identifier.issn2347-7946
dc.identifier.issn2347-7962
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/247729
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber4en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.4103/mgmj.mgmj_317_24en_US
dc.subjectEpilepsyen_US
dc.subjectnanocarrieren_US
dc.subjectnanosensorsen_US
dc.subjectnanotechnologyen_US
dc.subjectneurostimulation devicesen_US
dc.titleHarnessing nanotechnology for enhanced epilepsy managementen_US
dc.typeJournal Articleen_US
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