Cord Blood Bilirubin as a Predictor of Neonatal Hyperbilirubinemia

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dc.contributor.authorBeg, Samanen_US
dc.contributor.authorFirdaus, Uzmaen_US
dc.contributor.authorAli, Syed Manaziren_US
dc.date.accessioned2025-05-09T10:44:59Z
dc.date.available2025-05-09T10:44:59Z
dc.date.issued2024-09
dc.description.abstractIntroduction: In the 1st week of life, hyperbilirubinemia is the most common clinical condition in newborns that has to be evaluated and treated. It is also a prominent cause of readmission to the hospital. Some newborns experience noticeable, potentially dangerous bilirubin levels, which can directly increase the risk of severe brain damage, despite it being a benign, postnatal, transitory phenomenon. The current investigation looked at the relationship between cord blood bilirubin levels and the predictability of pathological jaundice. Materials and Methods: Cord blood bilirubin was estimated at birth. Bilirubin estimation was done at 48 h, 72 h, and 5–7 days of life using a trans?bilirubinometer. The study was approved by the Institutional Ethical Committee. Results: Significant hyperbilirubinemia was found in 3.7% of the neonates. A statistically significant correlation was found between cord blood bilirubin and the development of significant hyperbilirubinemia at 48 h of life. Gender, gestational age, birth weight, and use of Oxytocin have no correlation with cord bilirubin or the subsequent development of jaundice. A cord blood value of >2 mg/dL has a high negative predictive value (98%), sensitivity (83%), specificity (41%), and positive predictive value (5.3%) in predicting the future development of future pathological jaundice. Conclusions: A high negative predictive value in our study suggests that healthy term babies with cord bilirubin ?2 mg/dL can be discharged early with assurance to parents. Babies with cord blood bilirubin >2 mg/dL should be followed more frequently.en_US
dc.identifier.affiliationsDepartment of Pediatrics, Career Institute of Medical Sciences and Hospital, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, J. N. Medical College and Hospital, AMU, Aligarh, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, J. N. Medical College and Hospital, AMU, Aligarh, Uttar Pradesh, Indiaen_US
dc.identifier.citationBeg Saman, Firdaus Uzma, Ali Syed Manazir . Cord Blood Bilirubin as a Predictor of Neonatal Hyperbilirubinemia. Acta Medica International. 2024 Sep; 11(3): 209-212en_US
dc.identifier.issn2349-0578
dc.identifier.issn2349-0896
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/245744
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber3en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.4103/amit.amit_46_24en_US
dc.subjectCord blood bilirubinen_US
dc.subjecthigh negative predictive valueen_US
dc.subjecthyperbilirubinemiaen_US
dc.subjecttrans?bilirubinometeren_US
dc.titleCord Blood Bilirubin as a Predictor of Neonatal Hyperbilirubinemiaen_US
dc.typeJournal Articleen_US
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