A study on clinical and laboratory features of pit viper envenomation from Central Kerala, India

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dc.contributor.authorP. T., Hijazen_US
dc.contributor.authorC. R., Anil Kumaren_US
dc.contributor.authorJohn, Bins M.en_US
dc.date.accessioned2020-04-09T07:40:04Z
dc.date.available2020-04-09T07:40:04Z
dc.date.issued2018-05
dc.description.abstractBackground: Snakebite envenomation is an important public health problem faced by the tropical countries with India, the worst affected in terms of mortality and morbidity. In spite of increasing reports of other snake species causing envenomation, the existing research and management strategies including antivenom are still focused on the “Big Four” species- Russel’s viper, saw scaled viper, common krait and spectacled cobra. Pit vipers as a group are being increasingly reported to cause human bites from different parts of the country. Hence, we decided to study the clinico-epidemiology of pit viper bites.Methods: 30 cases of proven pit viper bites who attended our Department during the study period of 18 months were analysed for the epidemiological factors, clinical features and abnormalities in laboratory parameters.Results: Hump nosed pit viper (Hypnale hypnale) was responsible for all the thirty cases. 57% of cases were females. Mean age of victims was 41.8 years. 17 patients had exclusively local envenomation. Ten cases had coagulopathy along with local envenomation. Three patients developed acute kidney injury of whom three underwent dialysis. No mortality was observed in the study. Low fibrinogen levels were observed in all cases with coagulopathy and some had low levels of factor V (70%) and factor VIII (40%).Conclusions: Hump nosed viper bites were observed to be common in this part of the country. Significant envenomation can occur. Further epidemiologic studies involving more centres will be helpful in quantifying the true incidence of bites. Since no specific antivenom is available, further researches in this direction are warranted.en_US
dc.identifier.affiliationsDepartment of Medicine, Jubilee Mission Medical College and Research Institute Thrissur, Kerala, Indiaen_US
dc.identifier.citationP. T. Hijaz, C. R. Anil Kumar, John Bins M.. A study on clinical and laboratory features of pit viper envenomation from Central Kerala, India. International Journal of Advances in Medicine. 2018 May; 5(3): 644-651en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/193994
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20182117en_US
dc.subjectEnvenomationen_US
dc.subjectHypnale hypnaleen_US
dc.subjectPit viperen_US
dc.titleA study on clinical and laboratory features of pit viper envenomation from Central Kerala, Indiaen_US
dc.typeJournal Articleen_US
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