Elicitation effect on the production of asiaticoside and asiatic acid in shoot, callus, and cell suspension culture of Centella asiatica

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dc.contributor.authorKrishnan, M. Laxmien_US
dc.contributor.authorRoy, Arpitaen_US
dc.contributor.authorBharadvaja, Navneetaen_US
dc.date.accessioned2020-10-16T08:55:36Z
dc.date.available2020-10-16T08:55:36Z
dc.date.issued2019-06
dc.description.abstractCentella asiatica is an important medicinal plant which contains various phytocompounds. Asiatic acid and asiaticosideare two major compounds which are responsible for its various pharmaceutical activities. The present study analyzesthe effect of elicitor, i.e., methyl jasmonate on the synthesis of asiaticoside and asiatic acid (ATA) in shoot, callus, andcell suspension cultures of C. asiatica. A high-performance liquid chromatography analysis showed that the elicitationwith 100 µM concentration of methyl jasmonate enhanced asiaticoside content by 69-fold in callus culture, 39-fold inshoot cultures, and ATA by 1.9-fold in cell suspension culture. Thus, elicitation with methyl jasmonate is an effectivemethod of increasing the rate of biosynthesis of asiaticoside and ATA in plant cell cultures of C. asiaticaen_US
dc.identifier.affiliationsDelhi Technological University, Shahbad Daulatpur, Delhi, India.en_US
dc.identifier.citationKrishnan M. Laxmi, Roy Arpita, Bharadvaja Navneeta. Elicitation effect on the production of asiaticoside and asiatic acid in shoot, callus, and cell suspension culture of Centella asiatica. Journal of Applied Pharmaceutical Science. 2019 Jun; 2019 Jun: 067-074en_US
dc.identifier.issn2231-3354
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/210388
dc.languageenen_US
dc.publisherOpen Science Publishers LLPen_US
dc.relation.issuenumber6en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.7324/JAPS.2019.90609en_US
dc.subjectCentella asiaticaen_US
dc.subjectasiaticosideen_US
dc.subjectasiatic aciden_US
dc.subjectcell suspension cultureen_US
dc.subjectmethyl jasmonateen_US
dc.subjectshoot cultures.en_US
dc.titleElicitation effect on the production of asiaticoside and asiatic acid in shoot, callus, and cell suspension culture of Centella asiaticaen_US
dc.typeJournal Articleen_US
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