Diminished LC3 expression with unchanged Beclin 1 levels in right atrial appendage tissue of diabetic patients undergoing coronary artery bypass graf

Simple item page
dc.contributor.authorRajendran, RSen_US
dc.contributor.authorJayakumari, NRen_US
dc.contributor.authorPillai, VVen_US
dc.contributor.authorKarunakaran, Jen_US
dc.contributor.authorGopala, Sen_US
dc.date.accessioned2024-12-07T11:14:11Z
dc.date.available2024-12-07T11:14:11Z
dc.date.issued2024-01
dc.description.abstractType 2 diabetes potentiates the risk of heart failure. A vital physiologic process, autophagy, may be impaired in the diabetic heart. The purpose of the present work was to explore the autophagic status in the human diabetic heart. Techniques like immunohistochemistry and western blotting were employed to examine the expression of some of the important proteins involved in autophagic machinery. Our brief study reports, for the first time, evidence of decreased cardiac autophagic levels in diabetic patients.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Keralaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Keralaen_US
dc.identifier.affiliationsDepartment of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiovascular and Thoracic Surgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Keralaen_US
dc.identifier.citationRajendran RS, Jayakumari NR, Pillai VV, Karunakaran J, Gopala S. Diminished LC3 expression with unchanged Beclin 1 levels in right atrial appendage tissue of diabetic patients undergoing coronary artery bypass graf. Annals of the National Academy of Medical Sciences (India). 2024 Jan; 60(1): 30-33en_US
dc.identifier.issn0379-038X
dc.identifier.issn2454-5635
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/241074
dc.languageenen_US
dc.publisherNational Academy of Medical Sciencesen_US
dc.relation.issuenumber1en_US
dc.relation.volume60en_US
dc.source.urihttps://dx.doi.org/10.1055/s-0043-1772578en_US
dc.subjectAutophagyen_US
dc.subjectHearten_US
dc.subjectType 2 Diabetesen_US
dc.subjectCABGen_US
dc.subjectLC3en_US
dc.titleDiminished LC3 expression with unchanged Beclin 1 levels in right atrial appendage tissue of diabetic patients undergoing coronary artery bypass grafen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
anams2024v60n1p30.pdf
Size:
521.95 KB
Format:
Adobe Portable Document Format
Download
Collections
Annals of the National Academy of Medical Sciences (India)