INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) for Primary Care Physicians: Development and Validation.
Loading...
Date
2014-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Objective: To evaluate the diagnostic accuracy of a new
diagnostic instrument for epilepsy – INCLEN Diagnostic Tool for
Epilepsy (INDT-EPI) – with evaluation by expert pediatric
neurologists.
Study design: Evaluation of diagnostic test.
Setting: Tertiary care pediatric referral centers in India.
Methods: Children aged 2-9 years, enrolled by systematic
random sampling at pediatric neurology out-patient clinics of
three tertiary care centers were independently evaluated in a
blinded manner by primary care physicians trained to administer
the test, and by teams of two pediatric neurologists.
Outcomes: A 13-item questionnaire administered by trained
primary care physicians (candidate test) and comprehensive
subject evaluation by pediatric neurologists (gold standard).
Results: There were 240 children with epilepsy and 274 without
epilepsy. The candidate test for epilepsy had sensitivity and
specificity of 85.8% and 95.3%; positive and negative predictive
values of 94.0% and 88.5%; and positive and negative likelihood
ratios of 18.25 and 0.15, respectively.
Conclusion: The INDT-EPI has high validity to identify children
with epilepsy when used by primary care physicians.
Description
Keywords
Childhood neuro-developmental disorders, Resource-limited settings, Psychometric evaluations
Citation
Konanki Ramesh, Mishra Devendra, Gulati Sheffali, Aneja Satinder, Deshmukh Vaishali, Silberberg Donald, Pinto Jennifer M, Durkin Maureen, Pandey Ravindra M, Nair M K C, Arora Narendra K. INCLEN Diagnostic Tool for Epilepsy (INDT-EPI) for Primary Care Physicians: Development and Validation. Indian Pediatrics. 2014 July; 51(7): 539-543.