Treatment of acute infectious purpura fulminans with activated protein C.

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dc.contributor.authorLokeshwar, M Ren_US
dc.contributor.authorSinghal, Ten_US
dc.contributor.authorUdani, S Ven_US
dc.contributor.authorKapadia, F Nen_US
dc.date.accessioned2006-06-06en_US
dc.date.accessioned2009-05-27T05:10:28Z
dc.date.available2006-06-06en_US
dc.date.available2009-05-27T05:10:28Z
dc.date.issued2006-06-06en_US
dc.description.abstractInfectious purpura fulminans is associated with high mortality and morbidity despite standard antimicrobial therapy. We report satisfactory clinical outcome in two children with sepsis associated purpura fulminans who were treated with activated protein C (APC). There is need for proper evaluation of the efficacy of this extremely expensive therapeutic modality by randomized controlled trials before it is made standard of care in childhood infectious purpura fulminans.en_US
dc.description.affiliationDepartment of Pediatrics, P.D. Hinduja National Hospital and Research Center, Veer Savarkar Marg, Mumbai 400 016, India.en_US
dc.identifier.citationLokeshwar MR, Singhal T, Udani SV, Kapadia FN. Treatment of acute infectious purpura fulminans with activated protein C. Indian Pediatrics. 2006 Jun; 43(6): 535-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/8826
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAnticoagulants --therapeutic useen_US
dc.subject.meshBlood Coagulation Factors --drug effectsen_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshProtein C --therapeutic useen_US
dc.subject.meshPurpura, Schoenlein-Henoch --drug therapyen_US
dc.subject.meshReceptors, Cell Surface --drug effectsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleTreatment of acute infectious purpura fulminans with activated protein C.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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