Pregnancy associated anemia and iron: a pilot study.

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dc.contributor.authorRani, N Ven_US
dc.contributor.authorPandey, Jen_US
dc.contributor.authorDas, Ben_US
dc.contributor.authorShruti,en_US
dc.contributor.authorTalib, V Hen_US
dc.contributor.authorSingh, Ken_US
dc.contributor.authorBagati, Aen_US
dc.date.accessioned1995-07-01en_US
dc.date.accessioned2009-05-29T12:05:29Z
dc.date.available1995-07-01en_US
dc.date.available2009-05-29T12:05:29Z
dc.date.issued1995-07-01en_US
dc.description.abstractIron deficiency occurs when the rate of loss of utilization exceeds its assimilation. Treatment is based on iron supplementation but due to side effects compliance to iron therapy is poor. A double blind comparative study was done using a novel time release preparation of ferrous sulphate (Code A) v.s. sustained release ferrous sulphate preparation (Code B) on 60 pregnant women in mid or late pregnancy with anaemia. The amount of ferrous sulphate in Code A was less than half of Code B. The patients were sequentially randomised as Code A or Code B recipient. The non compliance rate was 33%, and for both Code A & Code B. The mean improvement in hemoglobin after 4 weeks of therapy was 2.01 gm% for Code A and 2.3 gm% for Code B. Iron absorption as evidenced by improvement in S. Iron, TIBC and ferritin levels was better with Code A. The improvement in subjective symptoms of anaemia was better than average in Code B preparation. Code A group had comparatively more side effects both major and minor, this may have been the reason for a slightly higher drop out rate in this group. In conclusion the timed release preparation has a comparable haematological response and better absorption with significantly lower doses as compared to the sustained release preparation.en_US
dc.description.affiliationDepartment of Laboratory Medicine, Safdarjang Hospital, New Delhi.en_US
dc.identifier.citationRani NV, Pandey J, Das B, Shruti , Talib VH, Singh K, Bagati A. Pregnancy associated anemia and iron: a pilot study. Indian Journal of Pathology & Microbiology. 1995 Jul; 38(3): 293-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74219
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAnemia, Iron-Deficiency --drug therapyen_US
dc.subject.meshDelayed-Action Preparations --metabolismen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFemaleen_US
dc.subject.meshFerrous Compounds --administration & dosageen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Hematologic --drug therapyen_US
dc.titlePregnancy associated anemia and iron: a pilot study.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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