Frequency Distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent.

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dc.contributor.authorPennap, G R
dc.contributor.authorEnvoh, E
dc.contributor.authorIgbawua, I
dc.date.accessioned2015-08-31T09:19:11Z
dc.date.available2015-08-31T09:19:11Z
dc.date.issued2011-04
dc.description.abstractBackground: Hemoglobin variants, ABO and Rhesus blood groups are known to vary from one population to another. This study therefore sought to study the frequency of these indices among a cohort of Nigerian University students of African descent. The result will serve as a platform for instituting genetic counseling services with a view to reducing hemoglobinopathies. Methods: Two hundred consenting students were recruited and screened for hemoglobin variants by standard alkaline cellulose acetate electrophoresis. ABO and Rhesus blood groups were determined by the hemagglutination technique. Results: Of the 200 students aged 18 – 25 years that were screened, 123 (61.5%) were males and 77 (38.5%) were females. Those with blood group O were the most prevalent (45%) followed by groups A (25.5%), B (25%) and AB (3.5%). Only 2 genotypes HbAA (78.5%) and HbAS (21.5%) were reported in this study. Rhesus D antigen was positive for 94% and negative for 6% of the study population. Conclusion: The frequency of ABO and Rhesus blood groups appeared to be stable and consistent with reports from previous studies in Nigeria. Blood group O was the most prevalent. This also means there is a large pool of ‘’apparently’’ universal blood donors in this population. There was only one genotype variant reported (HbAS). This could imply a decline in hemoglobinopathies among Africans. Therefore the culture of genetic counseling must be encouraged and sustained.en_US
dc.identifier.citationPennap G R, Envoh E, Igbawua I. Frequency Distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent. British Microbiology Research Journal. 2011 Apr; 1(2): 33-40.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/162795
dc.language.isoenen_US
dc.source.urihttps://sciencedomain.org/abstract/70en_US
dc.subjectFrequencyen_US
dc.subjectblood groupsen_US
dc.subjectABOen_US
dc.subjectRhesusen_US
dc.subjectgenotypeen_US
dc.subjecthemoglobinopathiesen_US
dc.titleFrequency Distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent.en_US
dc.typeArticleen_US
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