Histoplasmosis in Africa: a review.

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dc.contributor.authorGugnani, H Cen_US
dc.date.accessioned2000-10-16en_US
dc.date.accessioned2009-05-27T10:26:50Z
dc.date.available2000-10-16en_US
dc.date.available2009-05-27T10:26:50Z
dc.date.issued2000-10-16en_US
dc.description57 references.en_US
dc.description.abstractClassical histoplasmosis caused by Histoplasma capsulatum var. capsulatum, and African histoplasmosis caused by H. capsulatum var. duboisii are both endemic in Africa. In South Africa, only classical histoplasmosis caused by Histoplasma capsulatum var. capsulatum is known to occur and cases are seen frequently. It occurs sporadically in several other African countries. Histoplasma capsulatum var. capsulatum is known to occur naturally in caves inhabited by bats in some parts of South Africa, namely, Transvaal and Cape province, Zimbabwe and Tanzania. Outbreaks of histoplasmosis have been reported in cave explorers. Surveys of histoplasmin skin sensitivity carried out in Africa have shown the rate of positive reactors to be from 0.0% to 28%. African histoplasmosis caused by H. capsulatum var. duboisii is prevalent in Western and Central Africa, and in the island of Madagascar between the Kalahari and Sahara deserts, that is between latitudes 20 degrees North and 20 degrees South of the Equator. A natural reservoir of this fungus in soil admixed with bat guano has been found in a bat cave in a rural area, viz. Ogbunike in Anambra State of Nigeria. The clinical features and epidemiology of the two forms of the disease in Africa are reviewed.en_US
dc.description.affiliationDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi. vpci@delnet.ren.nic.inen_US
dc.identifier.citationGugnani HC. Histoplasmosis in Africa: a review. The Indian Journal of Chest Diseases & Allied Sciences. 2000 Oct-Dec; 42(4): 271-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/30060
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/iae/iaem.shtmlen_US
dc.subject.meshAfrica --epidemiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChiroptera --microbiologyen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshDisease Reservoirsen_US
dc.subject.meshHistoplasmosis --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshZoonosesen_US
dc.titleHistoplasmosis in Africa: a review.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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