New insights into leukotrichia in nonsegmental vitiligo: A cross-sectional study

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dc.contributor.authorMogawer, Rania Men_US
dc.contributor.authorElmasry, Maha Fathyen_US
dc.contributor.authorMostafa, Wedad Zen_US
dc.date.accessioned2020-01-02T06:52:38Z
dc.date.available2020-01-02T06:52:38Z
dc.date.issued2019-07
dc.description.abstractBackground: Leukotrichia has been considered a predictor of poor outcome in vitiligo. However, studies considering the different clinical aspects of leukotrichia in vitiligo patients are few. Aim: Our aim was to conduct a detailed clinical study to provide insights into the relevance and associations of leukotrichia in non-segmental vitiligo. Methods: In this cross-sectional study, vitiligo patients attending the dermatology outpatient clinic and phototherapy unit at Cairo University Hospital over a period of 6 months (April–September 2016) were included. Family history, clinical details, the Vitiligo Global Issues Consensus Conference classification, the Dermatology Life Quality Index, Vitiligo Area and Severity Index, Vitiligo Extent Score, Vitiligo Disease Activity Score and Vellus Score were determined and these measurements were correlated to leukotrichia. Results: Out of the 101 patients studied, leukotrichia was found in 47 (46.5%) patients, with vellus hair involved in 37 (78.7%), terminal hairs in 30 (63.8%) and both in 20 (42.5%) patients. Vellus hair involvement was significantly higher in generalized bilaterally symmetrical vitiligo than in acrofacial or unclassified vitiligo. The incidence of scalp leukotrichia also was higher in generalized symmetrical vitiligo than in acrofacial vitiligo. The Vellus Score showed significant associations with Vitiligo Area and Severity Index, Vitiligo Extent Score and the Dermatology Life Quality Index. Limitations: This was a short-term study with a small sample size. Prognostic and therapeutic correlations were not studied; prospective longitudinal studies are needed for further evaluation. Conclusion: Leukotrichia was found in almost half of the studied sample and its frequency varied among the different types of vitiligo.en_US
dc.identifier.affiliationsDepartment of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypten_US
dc.identifier.citationMogawer Rania M, Elmasry Maha Fathy, Mostafa Wedad Z. New insights into leukotrichia in nonsegmental vitiligo: A cross-sectional study. Indian Journal of Dermatology, Venereology and Leprology. 2019 Jul; 85(4): 374-379en_US
dc.identifier.issn0378-6323
dc.identifier.issn0973-3922
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/192504
dc.languageenen_US
dc.publisherIndian Association of Dermatologists, Venereologists & Leprologistsen_US
dc.relation.issuenumber4en_US
dc.relation.volume85en_US
dc.source.urihttps://dx.doi.org/10.4103/ijdvl.IJDVL_49_18en_US
dc.subjectLeukotrichiaen_US
dc.subjectVellus Scoreen_US
dc.subjectvitiligoen_US
dc.subjectVitiligo Area and Severity Indexen_US
dc.subjectVitiligo Extent Scoreen_US
dc.titleNew insights into leukotrichia in nonsegmental vitiligo: A cross-sectional studyen_US
dc.typeJournal Articleen_US
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