Serum complement (C3, C4) levels in patients with acute myocardial infarction and angina pectoris.

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dc.contributor.authorGiasuddin, A S Men_US
dc.contributor.authorElMahdawi, Jamila Men_US
dc.contributor.authorElHassadi, Fakhri Men_US
dc.date.accessioned2007-12-12en_US
dc.date.accessioned2009-05-27T03:47:00Z
dc.date.available2007-12-12en_US
dc.date.available2009-05-27T03:47:00Z
dc.date.issued2007-12-12en_US
dc.descriptionBangladesh Medical Research Council Bulletin.en_US
dc.description.abstractSerum complement (C3, C4) levels in Libyan patients with acute myocardial infarction (AMI; 31 patients) and angina pectoris (AP; 11 patients) at the 1st day and 7th day of attack were estimated. A group of 26 healthy Libyans were taken as control subjects (CS). Serum C3 and C4 levels (mean +/- SD, mg/dl) were elevated at the 1st day in AMI as well as AP patients (C3 --> AMI1: 154.0 +/- 28.5, AP1: 152.0 +/- 45.0, CS: 132.0 +/- 8.0, ANOVA: p = 0.0072; C4 --> AMII1: 38 +/- 13, AP1: 37 +/- 17, CS: 29 +/- 6, ANOVA: p = 0.0160). No significant differences for the elevated C3 and C4 levels at the 1st day were observed between the two diseases groups (AMI1 vs AP1 --> C3: p = 0.879, C4: p = 0.818). At the 7th day, C3 and C4 levels were further elevated in AMI, while they remained at the similar elevated levels in AP (C3 --> AMI 7: 173.1 +/- 28.0, AP 7: 149.0 +/- 41.0, CS: 132.0 +/- 8.0, ANOVA: p = 0.0000; C4 --> AMI 7: 46.0 +/- 7.0, AP 7: 36.0 +/- 15.0, CS: 29.0 +/- 6.0, ANOVA: p = 0.0000). Again, no significance differences for the raised C3 and C4 levels at the 7th day was observed between AMI and AP patients (AMI 7 vs AP 7 --> C3: P = 0.059, C4: p = 0.06). The C3 elevation showed significant positive correlation in AMI group (r = 0.522, p = 0.003) while it was insignificant in AP patients (r = 0.037, p = 0.915). Regarding C4 levels, it was significantly correlated in AMI (r = 0.483, p = 0.006), and in AP, although it was positively correlated (r = 0.656, P = 0.028) the observed difference was not significant (t = 0.29, p = 0.778). In conclusion, serum C3 and C4 levels were more profoundly elevated in AMI compared to AP patients suggestive of an acute phase and inflammatory response.en_US
dc.description.affiliationDepartment of Laboratory Medicine, Al-Arab Medical University, Benghazi, Libya. asmgias@proshikanet.comen_US
dc.identifier.citationGiasuddin AS, ElMahdawi JM, ElHassadi FM. Serum complement (C3, C4) levels in patients with acute myocardial infarction and angina pectoris. Bangladesh Medical Research Council Bulletin. 2007 Dec; 33(3): 98-102en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219
dc.language.isoengen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/indexen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/article/view/1141/1153en_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshAngina Pectoris --blooden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshComplement C3 --analysisen_US
dc.subject.meshComplement C4 --analysisen_US
dc.subject.meshComplement Hemolytic Activity Assayen_US
dc.subject.meshFemaleen_US
dc.subject.meshHealth Surveysen_US
dc.subject.meshHumansen_US
dc.subject.meshLibyaen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyocardial Infarction --blooden_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshRisk Factorsen_US
dc.titleSerum complement (C3, C4) levels in patients with acute myocardial infarction and angina pectoris.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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