Pap test accuracy and severity of squamous intraepithelial lesion.
| dc.contributor.author | Cobucci, R N O | |
| dc.contributor.author | Maisonnette, M J A S | |
| dc.contributor.author | Macêdo, E J S | |
| dc.contributor.author | Santos Filho, F C | |
| dc.contributor.author | Rodovalho, P E F | |
| dc.contributor.author | Nóbrega, M M | |
| dc.contributor.author | Gonçalves, A K S | |
| dc.date.accessioned | 2016-08-30T07:56:33Z | |
| dc.date.available | 2016-08-30T07:56:33Z | |
| dc.date.issued | 2016-01 | |
| dc.description.abstract | BACKGROUND: Cytology smears and guided biopsies are the most widely used diagnostic standards for cervical cancer (CC) screening in the developing countries. AIM: To evaluate the performance of conventional cytology in estimating the presence and grade of cervical disease against the reference standard of histopathology. SETTINGS AND DESIGN: After primary screening for CC, directed biopsies were performed and compared with histopathology results. MATERIALS AND METHODS: Papanicolaou (Pap) smears and biopsies from 3194 women in the age group of 14‑98 years were included. Cytology results were provided by doctors who performed the cervical biopsies. STATISTICAL ANALYSIS: The accuracy of Pap smear was measured by sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) calculated using the statistical analysis program PSPP 0.7.8. RESULTS: The sensitivity of conventional cytology (Pap smear) for women with low‑grade cervical intraepithelial neoplasia or less serious lesions (CIN1‑) was 93% and specificity was 73%. The sensitivity and specificity of cytology for women with high‑grade cervical intraepithelial neoplasia or cancer (CIN2+) was 64% and 84%, respectively. CONCLUSION: Cytology is a sufficiently sensitive test for detection of cervical lesions and can be used as a primary testing tool to triage. | en_US |
| dc.identifier.citation | Cobucci RNO, Maisonnette MJAS, Macêdo EJS, Santos Filho FC, Rodovalho PEF, Nóbrega MM, Gonçalves AKS. Pap test accuracy and severity of squamous intraepithelial lesion. Indian Journal of Cancer. 2016 Jan-Mar; 53(1): 74-76. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/176784 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.indianjcancer.com/article.asp?issn=0019-509X;year=2016;volume=53;issue=1;spage=74;epage=76;aulast=Cobucci | en_US |
| dc.subject | Cancer | en_US |
| dc.subject | cytology | en_US |
| dc.subject | uterine cervical diseases | en_US |
| dc.title | Pap test accuracy and severity of squamous intraepithelial lesion. | en_US |
| dc.type | Article | en_US |