Interleukin-6 (IL-6) and tumour necrosis factor-alpha in open and laparoscopic cholecystectomy.

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dc.contributor.authorHaq, Zen_US
dc.contributor.authorRahman, Men_US
dc.contributor.authorSiddique, M Aen_US
dc.contributor.authorRoy, R Ken_US
dc.contributor.authorRahman, A Men_US
dc.contributor.authorKhatun, Men_US
dc.date.accessioned2004-07-31en_US
dc.date.accessioned2009-05-27T03:53:15Z
dc.date.available2004-07-31en_US
dc.date.available2009-05-27T03:53:15Z
dc.date.issued2004-07-31en_US
dc.descriptionMymensingh Medical Journal.en_US
dc.description.abstractInjury to the human body alters normal physiology across several systems and these alterations are proportional to the extent of the injury. Physiological response to minimally invasive surgery appears to be different than those of traditional open surgery. Acute phase protein response appears to be one example. The important cytokines that are known as major mediators of acute phase response are interleukin-6 and TNF-alpha. Thirty patients were studied in which 14 underwent open cholecystectomy and 16 laparoscopic cholecystectomy. Three blood samples were taken from each patient, one pre-operatively and 2 post operatively at 4 and 24 hours. Interleukin-6 and Tumour Necrosis Factor-alpha (TNF-alpha) were raised significantly in post operative blood sample in both groups but the rise was much more in open group than laparoscopic group. This suggest less stress response in laparoscopic group which also showed a direct effect on patient convalescence in terms of less pain, less analgesic requirement and shorter hospital stayen_US
dc.description.affiliationAssociate Professor of Surgery, Sylhet MAG Osmani Medical College.en_US
dc.identifier.citationHaq Z, Rahman M, Siddique MA, Roy RK, Rahman AM, Khatun M. Interleukin-6 (IL-6) and tumour necrosis factor-alpha in open and laparoscopic cholecystectomy. Mymensingh Medical Journal. 2004 Jul; 13(2): 153-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/1343
dc.language.isoengen_US
dc.subject.meshAcute-Phase Reaction --blooden_US
dc.subject.meshAdulten_US
dc.subject.meshCholecystectomy, Laparoscopic --adverse effectsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGallstones --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshInterleukin-6 --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRecovery of Functionen_US
dc.subject.meshTumor Necrosis Factor-alpha --metabolismen_US
dc.titleInterleukin-6 (IL-6) and tumour necrosis factor-alpha in open and laparoscopic cholecystectomy.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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