Neutrophil to Lymphocyte Ratio (NLR) as an Inflammatory Marker in Predicting Severity in Acute Ischemic Stroke Patients
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Date
2024-12
Journal Title
Journal ISSN
Volume Title
Publisher
THE INDIAN MEDICAL ASSOCIATION
Abstract
Background : Inflammation plays an important role in Acute Ischemic Stroke (AIS). Chemokines and cytokines releases from ischemic tissue and recruit peripheral circulating leukocytes mainly neutrophils into the brain which precipitate ischemic brain injury and increases stroke severity. Lymphocytes on the other hand represent the protective or regulatory component of inflammation which decreases due to increased release of cortisol in response to stress. Aims and Objectives : To find the role of Neutrophil to Lymphocyte Ratio (NLR) in predicting the severity in patients of AIS. Materials and Methods : This study included 100 patients of AIS admitted in Government Medical College and Hospitals, Kota with all relevant exclusion criteria. Peripheral blood sample was taken before initiating any treatment and CBC test was performed from which NLR was calculated. The ratio was then compared with healthy control group and also among patients of AIS . Results : Mean value of NLR in AIS patients was 3.44 which was higher than NLR of control group which was 1.89 (p=0.001). Conclusion : Thus, NLR is a cost effective, easy to calculate and newer inflammatory marker that can help in predicting severity of acute ischemic stroke score.
Description
Keywords
Acute Ischemic Stroke (AIS), Neutrophil to Lymphocyte Ratio (NLR)
Citation
Sharma Deepti, Nagar Gordhan Lal, Fageria Narendra, Mangal Anup Kumar, Kumar Pawan . Neutrophil to Lymphocyte Ratio (NLR) as an Inflammatory Marker in Predicting Severity in Acute Ischemic Stroke Patients. Journal of the Indian Medical Association. 2024 Dec; 122(12): 40-43