Burden of disease & molecular epidemiology of group A rotavirus infections in India.

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dc.contributor.authorRamani, Sasirekhaen_US
dc.contributor.authorKang, Gagandeepen_US
dc.date.accessioned2007-05-24en_US
dc.date.accessioned2009-05-27T08:00:43Z
dc.date.available2007-05-24en_US
dc.date.available2009-05-27T08:00:43Z
dc.date.issued2007-05-24en_US
dc.description65 references.en_US
dc.description.abstractRotavirus is the major cause of severe dehydrating diarrhoea in young children worldwide. Considerable research has been carried out on rotavirus disease in India. This review collated data from 46 epidemiological studies to determine rotavirus positivity rates and genotypes of infecting rotavirus strains from various settings in India. Studies on diarrhoea presenting to hospitals, neonatal rotavirus infections, symptomatic and asymptomatic infections in the community and nosocomial enteric infections were included. Rotavirus positivity rates varied greatly between different settings - diarrhoea hospitalizations (20%), neonatal infections (35%), symptomatic and asymptomatic infections in the community (15.1% and 6.3% respectively) and nosocomial enteric infections (22.5%). Among diarrhea hospitalizations, the commonest G types were G1 and G2 while commonest P types were P[8], P[6] and P[4]. Region specific neonatal infections by bovinehuman reassortants have been reported, in addition to several recently described unusual strains, which may be evidence of zoonotic infection and/or reassortment. The emergence of several new strains highlights the need for intensive strain surveillance before and after the introduction of a new vaccine.en_US
dc.description.affiliationDepartment of Gastrointestinal Sciences, Christian Medical College, Vellore, India.en_US
dc.identifier.citationRamani S, Kang G. Burden of disease & molecular epidemiology of group A rotavirus infections in India. Indian Journal of Medical Research. 2007 May; 125(5): 619-32en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/22914
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshCommunity-Acquired Infections --epidemiologyen_US
dc.subject.meshCost of Illnessen_US
dc.subject.meshCross Infection --epidemiologyen_US
dc.subject.meshDiarrhea --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshRotavirus --classificationen_US
dc.subject.meshRotavirus Infections --epidemiologyen_US
dc.titleBurden of disease & molecular epidemiology of group A rotavirus infections in India.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
dc.typeReviewen_US
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