Superior vena cava syndrome: presentation of 7 cases and literature review

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dc.contributor.authorIxtl醜uac, JGen_US
dc.contributor.authorM閚dez, EADen_US
dc.contributor.authorNez, IJen_US
dc.contributor.authorAchicanoy, DMPen_US
dc.contributor.authorRodr韌uez, ASen_US
dc.contributor.authorAvilez, JHR.en_US
dc.date.accessioned2024-11-30T05:56:11Z
dc.date.available2024-11-30T05:56:11Z
dc.date.issued2024-08
dc.description.abstractSuperior vena cava syndrome (SVCS) is the result of obstruction of venous flow through the SVC. Mortality due to SVCS is rare (0.3%); however, the median survival in patients with SVCS secondary to malignancy is 6 months. Extrinsic occlusion due to malignancy is the most common cause; however, intraluminal thrombosis secondary to central venous catheters and pacemaker wires represents 30% of cases. The SVC is the main drainage pathway for the head, neck, and upper torso region, so SVCS is characterized by facial and neck edema, dyspnea, and distension of the neck and chest veins. Symptoms vary depending on the severity, location, and speed of onset of the obstruction and the establishment of collateral veins. Diagnosis is based on clinical presentation and imaging studies such as chest angiotomography and digital subtraction venography (gold standard). Regarding treatment, radiation therapy and chemotherapy were considered first-line; however, nowadays endovascular therapy (ET) (angioplasty, stent placement, and catheter-directed thrombus extraction) has demonstrated higher success rates and lower recurrence rates. Surgical diversion is reserved for cases of extensive venous thrombosis or occlusion not amenable to ET. We conducted a literature review and described 7 cases of SVCS treated with successful ET and their main complications at the national cancer institute of Mexico. SVCS is a condition with a diagnostic challenge. Currently, the use of endovascular treatment through angioplasty and stent placement leads to immediate improvement in patients, thus establishing it as first-line treatment.en_US
dc.identifier.affiliationsDepartment of interventional Radiology, National Cancer Institute, Mexico City, Mexicoen_US
dc.identifier.affiliationsDepartment of interventional Radiology, National Cancer Institute, Mexico City, Mexicoen_US
dc.identifier.affiliationsDepartment of Interventional Radiology, General Hospital Dr. Manuel Gea Gonzalez, Mexico City, Mexicoen_US
dc.identifier.affiliationsDepartment of interventional Radiology, National Cancer Institute, Mexico City, Mexicoen_US
dc.identifier.affiliationsDepartment of interventional Radiology, National Cancer Institute, Mexico City, Mexicoen_US
dc.identifier.affiliationsDepartment of interventional Radiology, National Cancer Institute, Mexico City, Mexicoen_US
dc.identifier.citationIxtl醜uac JG, M閚dez EAD, Nez IJ, Achicanoy DMP, Rodr韌uez AS, Avilez JHR.. Superior vena cava syndrome: presentation of 7 cases and literature review . International Surgery Journal. 2024 Aug; 11(8): 1313-1319en_US
dc.identifier.issn2349-3305
dc.identifier.issn2349-2902
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/236387
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber8en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2349-2902.isj20242125en_US
dc.subjectSVC syndromeen_US
dc.subjectETen_US
dc.subjectStenten_US
dc.subjectAngioplasty balloonen_US
dc.subjectCatheter-directed thrombolysisen_US
dc.titleSuperior vena cava syndrome: presentation of 7 cases and literature reviewen_US
dc.typeJournal Articleen_US
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