Cardiac malignant lymphoma in severe combine immunodeficient mice.

Simple item page
dc.contributor.authorAftabuddin, Men_US
dc.contributor.authorIslam, Nen_US
dc.contributor.authorAlimuzzaman, Men_US
dc.contributor.authorKoiralla, T Ren_US
dc.contributor.authorHori, Yen_US
dc.date.accessioned1996-07-01en_US
dc.date.accessioned2009-05-27T04:26:29Z
dc.date.available1996-07-01en_US
dc.date.available2009-05-27T04:26:29Z
dc.date.issued1996-07-01en_US
dc.description.abstractExtranodal malignant lymphomas are known to occur with increased frequency in patients with human immunodeficiency virus infection. Although cardiac malignant lymphomas are rare, recently an increasing number of patients with acquired immune deficiency syndrome (AIDS) and cardiac lymphoma have been reported. To clarify the relationship between AIDS and cardiac lymphomas, we used 60 severe combine immunodeficient (SCID) mice as animal models in whom five different types of human lymphoma cell lines were injected. Primary lymphomas at the site of cell line injection developed within 14-30 days in 58 mice. Cardiac malignant lymphoma was detected in 10 cases (17%), among which tumour was macroscopically evident in 2. Tumour was present on the pericardial aspects of the heart extending into the myocardium in most cases, but no intracavitary lesion was observed. In one case, obstructive features were marked near the root of the great vessels by direct pressure of the growth. This study indicates that lymphomas have a predilection to invade the heart in immunocompromised conditions.en_US
dc.description.affiliationDepartment of Surgery, Okayama University Medical School, Japan.en_US
dc.identifier.citationAftabuddin M, Islam N, Alimuzzaman M, Koiralla TR, Hori Y. Cardiac malignant lymphoma in severe combine immunodeficient mice. Indian Heart Journal. 1996 Jul-Aug; 48(4): 368-70en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/5233
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCell Divisionen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Neoplasms --complicationsen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphoma, Non-Hodgkin --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, SCIDen_US
dc.subject.meshNeoplasm Transplantationen_US
dc.subject.meshSevere Combined Immunodeficiency --complicationsen_US
dc.subject.meshTumor Cells, Cultureden_US
dc.titleCardiac malignant lymphoma in severe combine immunodeficient mice.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Heart Journal