Verbal learning in schizophrenia in remission, first-degree relatives, and correlation to symptoms

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dc.contributor.authorChattopadhyay, Sen_US
dc.contributor.authorSingh, OPen_US
dc.contributor.authorGhosh, S.en_US
dc.date.accessioned2023-07-14T07:00:43Z
dc.date.available2023-07-14T07:00:43Z
dc.date.issued2021-12
dc.description.abstractBackground: Cognitive impairments are fundamental in schizophrenia with verbal memory impairments commonly occurring not only in patients but also in unaffected genetically susceptible individuals. Deficits in verbal memory produce difficulty in problem-solving, emotional distress, and worsening of daily life skills resulting in a poor quality of life. Objectives: This study aims to evaluate the verbal memory in unaffected first-degree relatives of patients of schizophrenia in comparison to healthy controls as well as patients of schizophrenia in remission and to find correlation to symptom domains. Methods: It was a hospital-based, descriptive, cross-sectional case-control study. Three groups (n=40, each group) of patients, first-degree relatives, and controls were taken. Subjects were screened for mental retardation and remission was ascertained in the patient group by the Positive and Negative Syndrome Scale (PANSS). Rye’s Auditory Verbal Learning (RAVL) test was used to assess verbal leaning. Results: Verbal memory impairments were significant both in patients and unaffected first-degree relatives. Further, these impairments showed a strong correlation to negative symptoms. Conclusion: Significant (p<0.05) verbal learning impairments were noted in patients and first-degree relatives which showed a correlation to negative symptoms.en_US
dc.identifier.affiliationsDepartment of Psychiatry, NRS Medical College, Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Health and Family Welfare, Government of West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Psychiatry, NRS Medical College, Kolkata, West Bengal, Indiaen_US
dc.identifier.citationChattopadhyay S, Singh OP, Ghosh S.. Verbal learning in schizophrenia in remission, first-degree relatives, and correlation to symptoms. Open Journal of Psychiatry & Allied Sciences. 2021 Dec; 12(2): 105-108en_US
dc.identifier.issn2394-2061
dc.identifier.issn2394-2053
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/218396
dc.languageenen_US
dc.publisherAcademy Publisheren_US
dc.relation.issuenumber2en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.5958/2394-2061.2021.00023.9en_US
dc.subjectRetentionen_US
dc.subjectRecallen_US
dc.subjectCognitive Deficiten_US
dc.subjectPsychosisen_US
dc.subjectMemory.en_US
dc.titleVerbal learning in schizophrenia in remission, first-degree relatives, and correlation to symptomsen_US
dc.typeJournal Articleen_US
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Open Journal of Psychiatry & Allied Sciences, Formerly DYSPHRENIA